Heparan sulfate depletion within pulmonary fibroblasts: Implications for elastogenesis and repair

Journal of Cellular Physiology

Volumn 192, Issue 3, 2002, Pages 294-303

  Buczek Thomas, Jo Ann ^a   Chu, Chia L ^a   Rich, Celeste B ^a   Stone, Phillip J ^a   Foster, Judith A ^a   Nugent, Matthew A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTIN; FIBROBLAST GROWTH FACTOR 2; GLYCOSAMINOGLYCAN; HEPARAN SULFATE; PANCREATIC ELASTASE; PROTEOHEPARAN SULFATE; TROPOELASTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL COMPOSITION; CELL SURFACE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ELASTIC TISSUE; ELASTOLYSIS; ENZYME MECHANISM; EQUILIBRIUM CONSTANT; EXTRACELLULAR MATRIX; FIBROBLAST CULTURE; LIGAND BINDING; LUNG FIBROBLAST; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEOGLYCAN SYNTHESIS; QUANTITATIVE ANALYSIS; RAT; SULFATION; SWINE; TISSUE REPAIR;

ANIMALS; CELLS, CULTURED; ELASTIN; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; GLYCOSAMINOGLYCANS; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; LUNG; PANCREATIC ELASTASE; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTORS, FIBROBLAST GROWTH FACTOR; SWINE; WOUND HEALING;

SUIDAE;

EID: 0036323505     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10135     Document Type: Article

References (54)

1. Chlorate-a potent inhibitor of protein sulfation in intact cells
2. Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells in vitro: Implications for a role of heparinase-like enzymes in the neovascular response
3. Biological roles of fibroblast growth factor-2
4. Basic fibroblast growth factor decreases elastin production by neonatal rat lung fibroblasts
5. Elastase-mediated release of heparan sulfate proteoglycans from pulmonary fibroblast cultures
6. Pulmonary fibroblasts: A model system for studying elastin synthesis
7. Biological functions of proteoglycans: Use of specific inhibitors of proteoglycan synthesis
8. The sulfate moieties of glycosaminoglycans are critical for the enhancement of beta-amyloid protein fibril formation
9. Determination of cellular number of endothelial cells in culture using acid phosphatase assay
10. Mechanical properties of reconstituted collagen fibrils. Influence of a glycosaminoglycan: Dermatan sulfate
11. Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding
12. Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition
13. Enzymatic degradation of glycosaminoglycans
14. Basic fibroblast growth factor binds its receptors, is internalized, and stimulates DNA synthesis in Balb/c3T3 cells in the absence of heparan sulfate
15. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue
16. A unique heparan sulfate in the nuclei of hepatocytes: Structural changes with the growth state of the cells
17. Local expression of bovine decorin by cell-mediated gene transfer reduces neointimal formation after balloon injury in rats
18. Role of extracellular matrix in the action of basic fibroblast growth factor: Matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis
19. Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor
20. Pulmonary fibroblasts: And in vitro model of emphysema
21. Effect of proteoglycans on type I collagen fibre formation
22. Elastogenesis in the developing chick lung is transcriptionally regulated
23. Syndecans, heparan sulfate proteoglycans, maintain the proteolytic balance of acute wound fluids
24. Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2
25. Retrovirally mediated expression of decorin by macrovascular endothelial cells. Effects on cellular migration and fibronectin fibrillogenesis in vitro
26. Glypican and biglycan in the nuclei of neurons and glioma cells: Presence of functional nuclear localization signals and dynamic changes in glypican during the cell cycle
27. Packaging of proteases and proteoglycans in the granules of mast cells and other hematopoietic cells. A cluster of histidines on mouse mast cell protease 7 regulates its binding to heparin serglycin proteoglycans
28. A sulfated proteoglycan aggregation factor mediates amyloid-beta peptide fibril formation and neurotoxicity
29. Degradation and repair of elastic fibers in rat lung interstitial fibroblast cultures
30. Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: A mechanism for cooperativity
31. Fibroblast growth factor-2
32. Cell surface heparan sulfate proteoglycans: Selective regulators of ligand-receptor encounters
33. Fibroblast growth factor-2 selectively stimulates angiogenesis of small vessels in arterial tree
34. Involvement of lung interstitial proteoglycans in development of hydraulic-and elastase-induced edema
35. A quantitative solid-state assay for identifying radiolabeled glycosaminoglycans in crude cell extracts
36. Crucial role of heparan sulfate proteoglycan (agrin) in beta-amyloid formation in Alzheimer's disease
37. Elastase release of basic fibroblast growth factor in pulmonary fibroblast cultures results in down-regulation of elastin gene transcription
38. Basic fibroblast growth factor decreases elastin gene transcription through an AP1/cAMP-response element hybrid site in the distal promoter
39. Regulation of heparan sulfate proteoglycan nuclear localization by fibronectin
40. Selective effects of sodium chlorate treatment on the sulfation of heparan sulfate
41. Neutrophil-mediated degradation of lung proteoglycans stimulation by tumor necrosis factor-alpha in sputum of patients with bronchiectasis
42. Co-sedimentation of chondroitin sulfate A glycosaminoglycans and proteoglycans with the cytolytic secretory granules of rat large granular lymphocyte (LGL) tumor cells, and identification of a mRNA in normal and transformed LGL that encodes proteoglycans
43. Repair of elastase-digested elastic fibers in acellular matrices by replating with neonatal rat-lung lipid interstitial fibroblasts or other elastogenic cell types
44. Regulated shedding of syndecan-1 and-4 ectodomains by thrombin and growth factor receptor activation
45. The microfibrillar proteins MAGP-1 and fibrillin-1 form a ternary complex with the chondroitin sulfate proteoglycan decorin
46. Posttranslational modifications of microfibril associated glycoprotein-1 (MAGP-1)
47. Ultrastructural localization and characterization of proteoglycans in human lung alveoli
48. Induction of emphysematous lesions in rat lung by β-D-xyloside, an inhibitor of proteoglycan synthesis
49. Proteoglycan changes in the extracellular matrix of lung tissue from patients with pulmonary emphysema
50. Endothelial cell-derived basic fibroblast growth factor: Synthesis and deposition into subendothelial extracellular matrix
51. Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon
52. Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans
53. Heparin and heparan sulphate are inhibitors of human leukocyte elastase
54. Glycosaminoglycans mediate the coacervation of human tropoelastin through dominant charge interactions involving lysine side chains