Pronounced, early increase in circulating leptin predicts lower weight gain during clozapine treatment

Journal of Clinical Psychopharmacology

Volumn 22, Issue 4, 2002, Pages 424-426

  Monteleone, Palmiero ^a   Fabrazzo, Michele ^a   Tortorella, Alfonso ^a   La Pia, Silvestro ^b   Maj, Mario ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Department of Mental Health   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; LEPTIN;

ADULT; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; CORRELATION ANALYSIS; DRUG EFFECT; FEMALE; HORMONE DETERMINATION; HUMAN; MALE; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHIZOPHRENIA; WEIGHT GAIN;

ADULT; ANALYSIS OF VARIANCE; ANTIPSYCHOTIC AGENTS; CLOZAPINE; FEMALE; HUMANS; LEPTIN; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SCHIZOPHRENIA; STATISTICS, NONPARAMETRIC; WEIGHT GAIN;

EID: 0036321439     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004714-200208000-00015     Document Type: Article

References (6)

1. Atypical antipsychotics and weight gain: A systematic review
2. Neuroendocrine mechanisms regulating food intake and body weight
3. Serum leptin levels increase rapidly after initiation of clozapine therapy
4. Body weight and leptin plasma levels during treatment with antipsychotic drugs
5. A low serum leptin level at baseline and a large early decline in leptin predict a large 1-year weight reduction in energy-restricted obese humans
6. Manual for Expanded Brief Psychiatric Rating Scale (BPRS)