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Volumn 10, Issue 9, 2002, Pages 2873-2882

Pyridazines. Part XXIX: Synthesis and platelet aggregation inhibition activity of 5-substituted-6-phenyl-3(2H)-pyridazinones. Novel aspects of their biological actions

(7) Sotelo, Eddy a Fraiz, Nuria a Yáez, Matilde a Terrades, Vicente a Laguna, Reyes a Cano, Ernesto a Ravia, Enrique a

a UNIVERSITY OF SANTIAGO DE COMPOSTELA (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHENYL 3(2H) PYRIDAZINONE; ANTITHROMBOCYTIC AGENT; PYRIDAZINE DERIVATIVE; UNCLASSIFIED DRUG; 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CALCIUM; PHOSPHODIESTERASE III; PHOSPHODIESTERASE INHIBITOR;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; THROMBOCYTE AGGREGATION INHIBITION; ANIMAL; CHEMISTRY; CYTOSOL; DOSE RESPONSE; DRUG EFFECT; GUINEA PIG; IC 50; KINETICS; METABOLISM; PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THROMBOCYTE;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BLOOD PLATELETS; CALCIUM; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; PHOSPHODIESTERASE INHIBITORS; PHOSPHORYLATION; PLATELET AGGREGATION INHIBITORS; PYRIDAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036314584 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(02)00146-3 Document Type: Article

Times cited : (90)

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