Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-κB binding to the TNF promoter region [5]

Rheumatology

Volumn 41, Issue 7, 2002, Pages 830-831

  Udalova, I A ^a   Richardson, A ^a   Ackerman, H ^a   Wordsworth, P ^a   Kwiatkowski, D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; HLA DR4 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR;

ALLELE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG TARGETING; GENOTYPE; HEREDITY; HUMAN; JOINT PROSTHESIS; LETTER; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MONOCYTE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR GENE; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; SYNOVIUM;

ARTHRITIS, RHEUMATOID; DNA; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-DR ANTIGENS; HUMANS; NF-KAPPA B; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0036312203     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (5)

1. Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial
2. Efficient adenoviral infection with IkappaBalpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent
3. Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese
4. Functional consequences of genetic variation in NK-kappaB p50/p50 binding to the TNF promoter region
5. Polymorphisms in the 5′-flanking region of tumor necrosis factor-alpha gene in patients with rheumatoid arthritis