Congenital long QT syndrome with functionally impaired atrioventricular conduction: Successful treatment by mexiletine and propranolol

Journal of the Formosan Medical Association

Volumn 101, Issue 4, 2002, Pages 291-293

  Yao, Chih Ta ^a   Wang, Jieh Neng ^a   Tsai, Yu Chien ^a   Lin, Chia Shiang ^a   Wu, Jing Ming ^a  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Atrioventricular block; Congenital heart disease; Long QT syndrome

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; LIDOCAINE; MEXILETINE; PROPRANOLOL; SODIUM CHANNEL BLOCKING AGENT;

ARTICLE; ARTIFICIAL HEART PACEMAKER; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR CONDUCTION; CASE REPORT; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; FOLLOW UP; HEART RIGHT BUNDLE BRANCH BLOCK; HEART VENTRICLE TACHYCARDIA; HOLTER MONITORING; HUMAN; LONG QT SYNDROME; MALE; NEWBORN; QRS COMPLEX; QT INTERVAL; SIBLING; SINUS BRADYCARDIA; SUDDEN DEATH; SYMPTOMATOLOGY; T WAVE; TORSADE DES POINTES;

DRUG THERAPY, COMBINATION; HEART BLOCK; HUMANS; INFANT, NEWBORN; LONG QT SYNDROME; MALE; MEXILETINE; PROPRANOLOL;

EID: 0036302646     PISSN: 09296646     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. The long QT syndrome: Prospective longitudinal study of 328 families
2. Two: One atrioventricular block in infants with congenital long QT syndrome
3. Persistent functional atrioventricular block in two patients with prolonged QT intervals: Elucidation of the mechanism of block
4. Infants with long-QT syndrome and 2:1 atrioventricular block
5. Long QT syndrome manifested as fetal ventricular tachycardia and intermittent AV block
6. The long QT syndrome with impaired atrioventricular conduction: A malignant variant in infants
7. Two-to-one AV block associated with the congenital long QT syndrome
8. The long QT syndromes: Genetic basis and clinical implications
9. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de points in LQT2 and LQT3 models of the long QT syndrome
10. + channel blockade and to increases in heart rate: Implications for gene-specific therapy
11. Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: Effects of β-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes
12. ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome