Interactions of protein complexes on supercoiled DNA: The mechanism of selective synapsis by Tn3 resolvase

Journal of Molecular Biology

Volumn 319, Issue 2, 2002, Pages 371-383

  Brown, J Lesley ^a   He, Jiuya ^a   Sherratt, David J ^a   Marshall Stark, W ^a   Boocock, Martin R ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Looping; Resolvase; Site specific recombination; Supercoiled DNA; Synapsis

Indexed keywords

DNA; PROTEIN; RESOLVASE; TN3 RESOLVASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHROMOSOME PAIRING; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA SUPERCOILING; MODEL; MOLECULAR DYNAMICS; MOLECULE; MOTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; STEADY STATE;

EID: 0036301458     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00309-1     Document Type: Article

References (42)

1. Multipartite genetic control elements: Communication by DNA loop
2. DNA looping
3. Action at a distance: DNA-looping and initiation of transcription
4. Topological selectivity in site-specific recombination
5. Transposon-mediated site-specific recombination: A defined in vitro system
6. Site-specific relaxation and recombination by the Tn3 resolvase: Recognition of the DNA path between oriented res sites
7. Topological specificity in Tn3 resolvase catalysis
8. The Cre-lox recombination system
9. Catenation and supercoiling in the products of bacteriophage λ integrative recombination in vitro
10. The stereostructure of knots and catenanes produced by phage λ integrative recombination: Implications for mechanism and structure
11. FLP site-specific recombinase of yeast 2-μm plasmid: Topological features of the reaction
12. Supercoiled DNA-directed knotting by T4 topoisomerase
13. The resolvase protein from the transposon Tn21
14. Mechanism of Tn3 resolvase recombination in vivo
15. Determinants of correct res site alignment in site-specific recombination by Tn3 resolvase
16. Mutants of Tn3 resolvase which do not require accessory binding sites for recombination activity
17. Tn3 and related transposable elements: Site-specific recombination and transposition
18. Resolvase-mediated site-specific recombination
19. Recombination site selection by Tn3 resolvase: Topological tests of a tracking mechanism
20. Type III restriction endonucleases translocate DNA in a reaction driven by recognition site-specific ATP hydrolysis
21. Site-specific recombination by Tn3 resolvase: Models for pairing of recombination sites
22. DNA-directed synapsis in recombination: Slithering and random collision of sites
23. Communications between distant sites on supercoiled DNA from non-exponential kinetics for DNA synapsis by resolvase
24. Random walk models for DNA synapsis by resolvase
25. Stereoselectivity of DNA catenane fusion by resolvase
26. Internal motion of supercoiled DNA: Brownian dynamics simulations of site juxtaposition
27. Dynamics of site juxtaposition in supercoiled DNA
28. Diffusion-controlled intrachain reactions of supercoiled DNA: Brownian dynamics simulations
29. Intrachain reactions of supercoiled DNA simulated by Brownian dynamics
30. Dynamics of long-range interactions on DNA: The speed of synapsis during site-specific recombination by resolvase
31. Characterisation of the synaptic intermediate in site-specific recombination by Tn3 resolvase
32. Site-specific recombination by Tn3 resolvase: Topological changes in the forward and reverse reactions
33. DNA supercoiling determines the activation energy barrier for site-specific recombination by Tn21 resolvase
34. Isolation and characterisation of the Tn3 resolvase synaptic intermediate
35. Transposon-mediated site-specific recombination: Identification of three binding sites for resolvase at the res sites of γδ and Tn3
36. Transposon-encoded site-specific recombination: Nature of the Tn3 DNA sequences which constitute the recombination site res
37. Recombination by resolvase is inhibited by lac repressor simultaneously binding operators between res sites
38. Synapsis of Tn3 recombination sites: Unpaired sites destabilize synapses by a partner exchange mechanism
39. The apical localization of transcribing RNA polymerases on supercoiled DNA prevents their rotation around the template
40. Complete nucleotide sequence of the Escherichia coli plasmid pBR322
41. Tn3 resolvase catalyses multiple recombination events without intermediate rejoining of DNA ends