Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice

Biochemical and Biophysical Research Communications

Volumn 292, Issue 4, 2002, Pages 999-1009

  Morimoto, Ko ichi ^a,b   Shimizu, Takahiko ^a   Morio, Hidenori ^a,b   Shirasawa, Takuji ^a   Kurosawa, Hisashi ^b   Furukawa, Kiyoshi ^c  

^a Department of Molecular Genetics ^*  (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Bone formation; EXT2; Heparan sulfate; Hereditary multiple exostoses; Transgenic mouse

Indexed keywords

BETA GALACTOSIDASE; GLYCOSYLTRANSFERASE; HEPARAN SULFATE; PROTEIN; PROTEIN EXT1; PROTEIN EXT2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; BONE DEVELOPMENT; CARTILAGE CELL; CELL MATURATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HEREDITARY MULTIPLE EXOSTOSIS; HISTOPATHOLOGY; MOUSE; NEWBORN; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRABECULAR BONE; TRANSGENIC MOUSE;

ERINACEIDAE; MUS MUSCULUS;

EID: 0036298074     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6770     Document Type: Article

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