Immunohistochemical localization of the Ca2+ binding S100 proteins in normal human skin and melanocytic lesions

British Journal of Dermatology

Volumn 137, Issue 1, 1997, Pages 39-43

  Boni R ^a,b   Burg, G ^a   Doguoglu, A ^a   Ilg, E C ^a   Schafer B W ^a   Muller B ^a   Heizmann, C W ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM BINDING PROTEIN; POLYCLONAL ANTIBODY; PROTEIN S 100; RECOMBINANT PROTEIN; MONOCLONAL ANTIBODY; TUMOR PROTEIN;

ARTICLE; CONTROLLED STUDY; EPIDERMIS; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; LANGERHANS CELL; MELANOCYTE; MELANOMA; METASTASIS; NEVUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; SWEAT GLAND; CHEMISTRY; SKIN TUMOR;

ANTIBODIES, MONOCLONAL; HAIR FOLLICLE; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; NEOPLASM PROTEINS; NEVUS; S100 PROTEINS; SKIN; SKIN NEOPLASMS;

EID: 0030610328     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.1997.tb03698.x     Document Type: Article

References (20)

1. Schäfer BW, Heizmann CW. The S100 family of EF-hand calciumbinding proteins: functions and pathology. Trends Biochem Sci 1996; 21: 134-40.
2. Ilg EC, Schäfer BW, Heizmann CW. Expression pattern of S100 calcium-binding proteins in human tumors. Int J Cancer 1996; 67: 1-8.
3. Föhr UG, Heizmann CW. Engelkamp D et al. Purification and cation binding properties of the recombinant human S100 calcium-binding protein A3. an EF-hand motif protein with high affinity for zinc. J Biol Chem 1995; 270: 21056-61.
4. Cordell JL, Falini B, Erber WN et al. Immunoenzymatic labelling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem 1984; 32: 219-29.
5. Kernohan NM. Rankin R. S-100 protein: A prognostic indicator in cutaneous malignant melanoma. Histopathology 1987; 11: 1285-93.
6. Cho KH, Hashimoto K, Taniguchi Y et al. Immunohistochemical study of melanocytic nevus and malignant melanoma with monoclonal antibodies against S-100 subunits. Cancer 1990; 66: 765-71.
7. Rode J, Bhillon AP. Neurone specific enolase and S-100 protein as possible prognostic indicators in melanoma. Histopathology 1984; 8: 1041-52.
8. 2+-binding proteins of the S100 family in malignant human breastcancer cell lines and biopsy samples. Int J Cancer 1994; 57: 684-90.
9. Weterman MAJ, Stoopen GM, Muijen GNP et al. Expression of calcyclin in human melanoma cell lines correlates with metastatic behaviour in nude mice. Cancer Res 1992; 52: 1291-6.
10. Barraclough R, Savin J, Dube SK. Rudland PS. Molecular cloning and sequence of the gene for p9Ka. A cultured myoepithelial cell protein with strong homology to S-100, a calcium-binding protein. J Mol Biol 1987; 198: 13-20.
11. 2+-binding protein family. Genes Dev 1989; 3: 1086-93.
12. Goto K, Endo H, Fujiyoshi T, Cloning of the sequences expressed abundantly in established cell lines: identification of a cDNA clone highly homologous to S-100. a calcium-binding protein. J Biochem 1988; 103: 48-53.
13. Hilt DC, Kligman D, Novel Calcium-Binding Proteins: Fundamentals and Clinical Implications (Heizmann CW. ed.). Berlin: Springer-Verlag. 1991: 65-103.
14. Lee SW, Tomasello C, Swissholm K et al. Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment. Proc Natl Acad Sci USA 1992; 89: 2504-8.
15. Rothnagel JA, Rogers GE. Trichohyalin, an intermediate filament-associated protein of the hair follicle. J Cell Biol 1986; 102: 1419-29.
16. Weterman MA, Stoopen GM, van Muijen GN et al. Expression of calcyclin in human melanoma cell lines correlates with metastatic behavior in nude mice. Cancer Res 1992; 52: 1291-6.
17. Clark WH Jr. A classification of malignant melanoma in man correlated with histogenesis and biologic behavior. In: Advances of Biology of the Skin: The Pigmentary System. Vol. 8 (Montagna W. Hu F. eds). London: Pergamon Press, 1967: 621.
18. Guo XJ, Chambers AF, Parfett CL et al. Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, rastransformed NIH 3t 3 cells. Cell Growth Differ 1990; 1: 333-8.
19. 2+ -binding proteins S100A6 and S100B in primary cutaneous melanoma. J Cutan Pathol 1997; 26: 76-80.
20. Cochran AJ, Lu HF, Li PX et al. S-100 protein remains a practical marker for melanocytic and other tumours. Melanoma Res 1993; 3: 325-30.