Synthesis of new 3-methylthio-5-aryl-4-isothiazolecarbonitriles with broad antiviral spectrum

Antiviral Research

Volumn 55, Issue 2, 2002, Pages 357-368

  Cutri C C C ^a   Garozzo, A ^a   Siracusa, M A ^a   Castro, A ^a   Tempera, G ^a   Sarva M C ^a   Guerrera, F ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Isothiazole derivatives; Measles; Picornavirus

Indexed keywords

3 METHYLTHIO 5 [4 (2 PHENOXY 1 ETHOXY)PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 (2 PHENYL 1 ETHOXY)PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 (3 PHENOXY 1 PROPOXY)PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 (3 PHENYL 1 PROPOXY)PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 (4 PHENOXY 1 BUTOXY)PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [2 (4 CYANOPHENOXY) 1 ETHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [2 (4 ETHOXYCARBONILEPHENOXY) 1 ETHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [2 (4 NITROPHENOXY) 1 ETHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [3 (4 CYANOPHENOXY) 1 PROPOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [3 (4 ETHOXYCARBONILEPHENOXY) 1 PROPOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [3 (4 NITROPHENOXY) 1 PROPOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [4 (4 CYANOPHENOXY) 1 BUTHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [4 (4 ETHOXYCARBONILEPHENOXY) 1 BUTHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; 3 METHYLTHIO 5 [4 [4 (4 NITROPHENOXY) 1 BUTHOXY]PHENYL] 4 ISOTHIAZOLECARBONITRILE; ACETONE; BROMINE DERIVATIVE; ISOTHIAZOLE DERIVATIVE; NITRILE; PIRODAVIR; UNCLASSIFIED DRUG;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; CARDIOVIRUS; CONTROLLED STUDY; COXSACKIE VIRUS B; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ECHO VIRUS; ENTEROVIRUS; HERPES SIMPLEX VIRUS 1; IC 50; MEASLES VIRUS; NONHUMAN; PRIORITY JOURNAL; RHINOVIRUS; SEROTYPE; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; NITRILES; RHINOVIRUS; TEMPERATURE; THIAZOLES; TIME FACTORS; VIRUS REPLICATION;

CARDIOVIRUS; ENTEROVIRUS; HUMAN HERPESVIRUS 1; HUMAN RHINOVIRUS SP.; MEASLES VIRUS; PICORNAVIRIDAE; RHINOVIRUS; SIMPLEXVIRUS;

EID: 0036294707     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(02)00072-4     Document Type: Article

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