Synthesis and antiviral activity of a new series of 4-isothiazolecarbonitriles

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 12, 1998, Pages 2271-2280

  Cutrí, Christian C C ^a   Garozzo, Adriana ^a   Siracusa, Maria A ^a   Sarvá, Maria C ^a   Tempera, Gianna ^a   Geremia, Ernesto ^a   Pinizzotto, Maria R ^a   Guerrera, Francesco ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLTHIO 5 PHENYL 4 ISOTHIAZOLECARBONITRILE; ANTIVIRUS AGENT; ISOTHIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA VIRUS; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ECHO VIRUS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NONHUMAN; POLIOMYELITIS VIRUS; RNA VIRUS; STRUCTURE ACTIVITY RELATION;

ENTEROVIRUS; HUMAN POLIOVIRUS 1;

EID: 0032424801     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)80007-2     Document Type: Article

References (28)

1. Andries, K.; Dewindt, B.; Snoeks, J.; Willebrords, R.; Stokbroekx, R.; Lewi, P. J. Antiviral Res. 1991, 16, 213.
2. Andries, K.; Dewindt, B.; Snoeks, J.; Willebrords, R.; Van Eemeren, K.; Stokbroekx, R.; Janssen, P. A. J. Antimicrob. Agents Chemother. 1992, 36, 100.
3. Hayden, F. G.; Andries, K.; Janssen, P. A. J. Antimicrob. Agents Chemother. 1992, 36, 727.
4. Hayden, F. G.; Hipskind G. J.; Woerner, D. H.; Eisen, G. F.; Janssens, M.; Janssen, P. A. J.; Andries, K. Antimicrob. Agents Chemother. 1995, 39, 290.
5. Pinizzotto, M. R.; Garozzo, A.; Furneri, P. M.; Castro, A.; Geremia, E. J. Chemoth. 1991a, 3, 486.
6. Pinizzotto, M. R.; Garozzo, A.; Guerrera, F.; Castro, A.; La Rosa, M. G.; Furneri, P. M.; Geremia, E. Antiviral Res. 1992, 19, 29.
7. Garozzo, A.; Pinizzotto, M. R.; Guerrera, F.; Tempera, G.; Castro, A.; Geremia, E. Arch. Virol. 1994, 135, 1.
8. Hatchard, W. R. J. Org. Chem. 1964, 29, 660.
9. Hatchard, W. R. J. Org. Chem. 1964, 29, 665.
10. Crenshaw, R. R.; Essery, J. M.; Jeffries, A. T. J. Org. Chem. 1967, 32, 3132.
11. Micetich, R. G.; Raap, R. J. Med. Chem. 1968, 11, 159.
12. Naito, T.; Nakagawa, S.; Okumura, J.; Masuko, K. Bull. Chem. Soc. Japan 1968, 41, 957.
13. James, F. C.; Krebs, H. D. Aust. J. Chem. 1982, 35, 385.
14. Corson, B. B.; Stoughton, R. W. J. Am. Chem. Soc. 1928, 50, 2825.
15. Kim Y. C.; Hart, H. Tetrahedron 1969, 25, 3869.
16. Bilbo, R. E.; Boykin, D. W. J. Chem. Res. Synop. 1980, 9, 332.
17. Strell, M.; Kopp, E. Chem. Ber. 1958, 91, 2854.
18. Kompis, I.; Schonholzer, P. Helv. Chim. Acta 1977, 60, 618.
19. Nakagawa, S.; Okumura, J.; Sakai, F.; Hoshi, H.; Naito, T. Tetrahedron Lett. 1970, 42, 3719.
20. Hartke, K.; Peshkar, L. Angew. Chem. Int. Ed. Engl. 1967, 6, 83.
21. Pedersen, B. S.; Scheibye, S.; Klausen, K.; Lawesson, S. O. Bull. Soc. Chim. Belg. 1978, 87, 293.
22. Hartke, K.; Peshkar, L. Arch. Pharm. 1968, 301, 601.
23. Kiso, Y.; Ukawa, K.; Nakamura, S.; Ito, K.; Akita, T. Chem. Pharm. Bull. 1980, 28, 673.
24. Narasimhan, L.; Sanitra, R.; Swenton, J. S. J. Chem. Soc., Chem. Commun. 1978, 719.
25. Baxter, S. L.; Bradshaw, J. S. J. Org. Chem. Comm. 1981, 46, 831.
26. Budzikiewicz, H.; Lange, E.; Ockels, W. Phosphorus Sulfur 1981, 11, 33.
27. Mosmann, T. J. Immunol. Methods 1983, 65, 55.
28. Denizot, F.; Lang, R. J. Immunol. Methods 1986, 89, 271.