In the virion, the 11-amino-acid peptide cofactor pVIc is covalently linked to the adenovirus proteinase

Virology

Volumn 296, Issue 2, 2002, Pages 234-240

  McGrath, William J ^a   Aherne, Katharine S ^a   Mangel, Walter F ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DISULFIDE; PEPTIDE; PROTEINASE;

ADENOVIRUS; ARTICLE; ARTIFACT; CHEMICAL BOND; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; STIMULATION; VIRION; VIRUS PARTICLE;

ADENOVIRIDAE;

EID: 0036292317     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2002.1394     Document Type: Article

References (22)

1. Expression and purification of the adenovirus proteinase polypeptide and of a synthetic proteinase substrate
2. Interaction of the human adenovirus proteinase with its eleven amino-acid cofactor pVIc
3. Different modes of inhibition of human adenovirus proteinase, probably a cysteine proteinase, by bovine pancreatic trypsin inhibitor
4. Activation of the adenovirus protease requires sequence elements from both ends of the activating peptide
5. Crystal structure of the human adenovirus proteinase with its 11 amino-acid cofactor
6. Calculation of protein extinction coefficients from amino acid sequence data
7. The role of the adenovirus protease in virus entry into cells
8. Immobilon-P transfer membrane: Applications and utility in protein biochemical analysis
9. Viral DNA and a viral peptide can act as cofactors of adenovirus virion proteinase activity
10. Characterization of three components of human adenovirus proteinase activity in vitro
11. Human adenovirus proteinase: DNA binding and stimulation of proteinase activity by DNA
12. Roles of two conserved cysteine residues in the activation of human adenovirus proteinase
13. Polypeptide structure and encoding location of the serotype 2 adenovirus late, non-structural 33K protein
14. Proline 137 is critical for adenovirus protease encapsidation and activation but not enzyme activity
15. Ellman's reagent: 5,5′-Dithiobis(2-nitrobenzoic acid) - A reexamination
16. The effect of mutant peptide cofactors on adenovirus protease activity and virus infection
17. Protein blotting to nitrocellulose, nylon and PVDF membranes in immunoassays and electroblotting
18. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
19. Molecular composition of the adenovirus type 2 virion
20. Genetic analysis of adenovirus type 2. III. Temperature-sensitivity of processing of viral proteins
21. The adenovirus protease is activated by a virus-coded disulphide-linked peptide
22. Genetic identification of an endopeptidase encoded by the adenovirus genome