Molecular basis for stool-based DNA tests for colorectal cancer: A primer for clinicians

Reviews in Gastroenterological Disorders

Volumn 2, Issue SUPPL. 1, 2002, Pages

  Boland, C Richard ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

APC; Chromosomal instability; CIMP; Colon cancer; Genomic instability; Microsatellite instability; Mutation; Oncogene; p53; Tumor suppressor gene

Indexed keywords

DNA; MICROSATELLITE DNA;

ARTICLE; CELL FUNCTION; CELL SURVIVAL; CHROMOSOME ABERRATION; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DNA DETERMINATION; FECES ANALYSIS; GASTROINTESTINAL TRACT; GENE IDENTIFICATION; GENE INACTIVATION; GENE MUTATION; GENE TARGETING; GROWTH REGULATION; HUMAN; MICROSATELLITE INSTABILITY; MOLECULAR GENETICS; PHENOTYPIC VARIATION; TUMOR CELL; TUMOR SUPPRESSOR GENE; COLORECTAL TUMOR; DNA METHYLATION; DNA REPAIR; FECES; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MUTATION; PHENOTYPE; PHYSIOLOGY; REVIEW;

COLORECTAL NEOPLASMS; DNA METHYLATION; DNA REPAIR; DNA, NEOPLASM; FECES; GENES, TUMOR SUPPRESSOR; HUMANS; MICROSATELLITE REPEATS; MUTATION; PHENOTYPE;

EID: 0036290550     PISSN: 1533001X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Creation of human tumour cells with defined genetic elements
2. Allelotype of colorectal carcinomas
3. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
4. How many mutations does it take to make a tumor?
5. Microsatellites in the eukaryotic DNA mismatch repair genes as modulators of evolutionary mutation rate
6. Mutator phenotype may be required for multistage carcinogenesis
7. Lessons from hereditary colorectal cancer
8. Gatekeepers and caretakers
9. Genetic alterations during colorectal-tumor development
10. A genetic model for colorectal tumorigenesis
11. Microallelotyping defines the sequence and tempo of allelic losses at tumor suppressor gene loci during colorectal cancer progression
12. JC virus DNA is present in the human colon and in colorectal cancers
13. JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract
14. Genetic instability in colorectal cancers
15. Allelic loss in colorectal carcinoma
16. Microsatellite instability in cancer of the proximal colon
17. Clues to the pathogenesis of familial colorectal cancer
18. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
19. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
20. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
21. Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype