Ex vivo expanded peripheral blood progenitor cells provide rapid neutrophil recovery after high-dose chemotherapy in patients with breast cancer

Blood

Volumn 96, Issue 9, 2000, Pages 3001-3007

  McNiece, Ian ^a   Jones, Roy ^a   Bearman, Scott I ^a   Cagnoni, Pablo ^a   Nieto, Yago ^a   Franklin, Wilbur ^a   Ryder, John ^a   Steele, Andrea ^a   Stoltz, Judy ^a   Russell, Peggy ^a   McDermitt, Janet ^a   Hogan, Christopher ^a   Murphy, James ^a   Shpall, Elizabeth J ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CD34 ANTIGEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT STEM CELL FACTOR;

ARTICLE; BLOOD STORAGE; BREAST CANCER; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MEGADOSE; GRAFT SURVIVAL; HUMAN; LEUKOCYTE COUNT; NEUTROPENIA; NEUTROPHIL; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; THROMBOCYTE COUNT;

EID: 0034329327     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.9.3001     Document Type: Article

References (27)

1. Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants
2. Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy
3. Expansion of G-CSF mobilized CD34+ peripheral blood cells (PBC) for 10 days in G-CSF, MGDF and SCF prior to transplantation decreased post-transplant neutropenia in baboons
4. Clinical scale ex vivo expansion of myeloid progenitor cells and megakaryocytes under GMP conditions
5. Chronic myelogenous leukemia: In search of the benign hematopoietic stem cell
6. Culture purging in leukemia: Past, present, and future
7. Preferential expansion of hematopoietic versus acute leukemia cells ex vivo
8. Fate of contaminating t(14;18)+ lymphoma cells during ex vivo expansion of CD34-selected hematopoietic progenitor cells
9. Ex vivo expansion of CD34+ peripheral blood progenitor cell: Implications for the expansion of contaminating epithelial tumor cells
10. Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo
11. CD34-positive cells isolated from cryopreserved peripheral-blood progenitor cells can be expanded ex vivo and used for transplantation with little or no toxicity
12. Selection and expansion of peripheral blood CD34+ cells in autologous stem cell transplantation for breast cancer
13. A single apheresis combined with ex vivo expanded bone marrow cells from a small starting aliquot leads to rapid hematopoietic engraftment following autotransplantation
14. A randomized phase 3 study of PBPC mobilization by stem cell factor and filgrastim in patients with high-risk breast cancer
15. The ISHAGE guidelines for CD34+ cell determination by flow cytometry
16. Immunocytochemical detection of breast cancer cells in marrow and peripheral blood of patients undergoing high dose chemotherapy with autologous stem cell support
17. Use of freeze-dried paraffin-embedded sections for immunohistologic staining with monoclonal antibodies
18. Abrogation of post-myeloablative chemotherapy neutropenia by ex-vivo expanded CD34-positive cells
19. High CD34+ cell counts decrease hematologic toxicity of autologous peripheral blood progenitor cell transplantation
20. An analysis of engraftment kinetics as a function of CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy
21. Factors that influence collection and engraftment of autologous peripheral-blood stem cells
22. Positive selection of CD34+ hematopoietic progenitor cells for transplantation
23. Increased incidence of cytomegalovirus disease after autologous CD34-selected peripheral blood stem cell transplantation
24. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
25. Ex vivo expansion of PBPC maintains SCID repopulating cells and provides rapid and durable engraftment in breast cancer patients
26. Outcome of cord-blood transplantation from related and unrelated donors
27. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients