Interleukin-12 p40 gene expression is induced in lipopolysaccharide-activated pituitary glands in vivo

Neuroendocrinology

Volumn 75, Issue 6, 2002, Pages 347-357

  Yang, Young ^a   Han, Seung Hyun ^a   Kim, Hyun ^b   Kim, Changmee ^b   Kim, Kun Yong ^a   Shin, Sun Mi ^a   Choi, Inpyo ^a   Pyun, Kwang Ho ^c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

Author keywords

Catecholamine agonists; Hypothalamo pituitary adrenal axis; Interleukins; Lipopolysaccharide; Neuroimmune interactions

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CD14 ANTIGEN; CELL EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; PROTEIN P40; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS; IMMUNE SYSTEM; IN VIVO STUDY; MALE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION; STRESS;

ANIMALS; ANTIGENS, CD14; BLOTTING, NORTHERN; DNA; GENE EXPRESSION; IN SITU HYBRIDIZATION; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; LIPOPOLYSACCHARIDES; MALE; NF-KAPPA B; ORGAN CULTURE TECHNIQUES; PITUITARY GLAND; PITUITARY GLAND, ANTERIOR; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1;

EID: 0036284731     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000059431     Document Type: Article

References (42)

1. Stressors, stress, and neuroendocrine integration of the adaptive response
2. Endotoxin induces interleukin-1beta and nitric oxide synthase mRNA in rat hypothalamus and pituitary
3. Endotoxin-induced release of interleukin-6 from rat medial basal hypothalami
4. Tumor necrosis factor-alpha in macrophages of heart, liver, kidney, and in the pituitary gland
5. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
6. Acute stimulation of the hypothalamic-pituitary-adrenal axis by IL-1 beta, TNF alpha and IL-6: A dose response study
7. Synergism between IL-1 beta and TNF-alpha on the activity of the pituitary-adrenal axis and on food intake of rats
8. Tumor necrosis factor-alpha is a potent ACTH secretagogue: Comparison to interleukin-1 beta
9. Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
10. Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: Potential implications for the syndrome of inappropriate vasopressin secretion
11. Pituitary-dependent and -independent secretion of CS caused by bacterial endotoxin in rats
12. Lipopolysaccharide is able to bypass corticotrophin-releasing factor in affecting plasma ACTH and corticosterone levels: Evidence from rats with lesions of the paraventricular nucleus
13. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
14. Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia
15. Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia
16. Isoproterenol inhibits IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages
17. Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function
18. Induction of CREB activity via the surface Ig receptor of B cells
19. Oligonucleotide that binds nuclear factor NF-kappa B acts as a lymphoid-specific and inducible enhancer element
20. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated transacting factor
21. Electroconvulsive shock reduces inositol 1,4,5-triphosphate 3-kinase mRNA expression in rat dentate gyrus
22. Induction of interleukin-6 release by interleukin-1 in rat anterior pituitary cells in vitro: Evidence for an eicosanoid-dependent mechanism
23. NF-kappa B regulates the LPS-induced expression of interleukin 12 p40 in murine peritoneal macrophages: Roles of PKC, PKA, ERK, p38 MAPK, and proteasome
24. Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): Evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells
25. Increased interleukin-12 levels in human cerebrospinal fluid following severe head trauma
26. Acute endocrine effects of interleukin-12 in cancer patients
27. Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
28. Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide
29. Production of interleukin-6 by anterior pituitary cells in vitro
30. Induction of interferon-gamma inducing factor in the adrenal cortex
31. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor
32. Interleukin-1 stimulates ACTH release by an indirect action which requires endogenous corticotropin releasing factor
33. Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1
34. Induction of pituitary cytokine transcripts by peripheral lipopolysaccharide
35. Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS
36. Concomitant changes in CRH mRNA levels in rat hippocampus and hypothalamus following immobilization stress
37. Corticotropin-releasing hormone mediates the response to cold stress in the neonatal rat without compensatory enhancement of the peptide's gene expression
38. Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists
39. Regulation of interleukin-10 production by beta-adrenergic agonists
40. Modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by selective alpha- and beta-adrenergic drugs in mice
41. Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12
42. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: Clinical implications