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Volumn 16, Issue SUPPL. 1, 2002, Pages

Clinical trials in AD: Are current formats and outcome measures adequate?

Author keywords

Azheimer disease; Clinical outcomes; Clinical trials; Disease progression; Primary prevention

Indexed keywords

ALZHEIMER DISEASE; DISEASE COURSE; HUMAN; METHODOLOGY; PATHOPHYSIOLOGY; PRIMARY PREVENTION; PRIORITY JOURNAL; REVIEW; TREATMENT OUTCOME;

EID: 0036282820     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002093-200200001-00003     Document Type: Review
Times cited : (8)

References (53)
  • 3
    • 0025959748 scopus 로고
    • Tacrine as a treatment for Alzheimer's dementia: An interim report from the FDA
    • (1991) N Engl J Med , vol.324 , pp. 34-52
  • 4
    • 0033549101 scopus 로고    scopus 로고
    • The search for diagnostic and progression markers in AD: So near but still too far?
    • (1999) Neurology , vol.52 , pp. 1533-1534
    • Black, S.E.1
  • 7
    • 0030626839 scopus 로고    scopus 로고
    • Protocols to demonstrate slowing of Alzheimer disease progression. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines
    • The Disease Progression Sub-Group
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 3 , pp. 50-53
    • Bodick, N.1    Forette, F.2    Hadler, D.3
  • 10
    • 0033953342 scopus 로고    scopus 로고
    • Age-related cognitive decline, mild cognitive impairment or preclinical Alzheimer's disease?
    • (2000) Ann Med , vol.32 , pp. 6-14
    • Celsis, P.1
  • 11
    • 0031936729 scopus 로고    scopus 로고
    • A review of the randomised controlled trials of tacrine in the treatment of Alzheimer's disease: Methodologic considerations
    • (1998) Clin Neuropharmacol , vol.21 , pp. 8-17
    • Conway, E.L.1
  • 15
  • 18
  • 28
    • 0029938431 scopus 로고    scopus 로고
    • Rational design of an animal model for Alzheimer's disease: Introduction of multiple human genomic transgenes to reproduce AD pathology in a rodent
    • (1996) Neurobiol Aging , vol.17 , pp. 173-182
    • Loring, J.F.1    Paszty, C.2    Rose, A.3
  • 29
    • 0031683395 scopus 로고    scopus 로고
    • Outcome measures for clinical trials in Alzheimer's disease: A review on some open issues
    • (1998) Arch Gerontol Geriatr , vol.27 , Issue.SUPPL. 6 , pp. 295-300
    • Lucca, U.1
  • 33
    • 0030814418 scopus 로고    scopus 로고
    • Development of cognitive instruments for use in clinical trials of antidementia drugs: Additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 2
    • Mohs, R.C.1    Knopman, D.2    Petersen, R.C.3
  • 34
    • 0009486893 scopus 로고    scopus 로고
    • Nielsen/NetRatings. Internet penetration reaches 60% in the US. Press release, Feb. 14, 2001
  • 35
    • 0034087231 scopus 로고    scopus 로고
    • Mild cognitive impairment: Transition between aging and Alzheimer's disease
    • (2000) Neurologia , vol.15 , pp. 93-101
    • Petersen, R.C.1
  • 42
    • 0030861805 scopus 로고    scopus 로고
    • The Spanish Instrument Protocol: Design and implementation of a study to evaluate treatment efficacy instruments for Spanish-speaking patients with Alzheimer's disease. The Alzheimer's Disease Cooperative Study
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.SUPPL. 2
    • Sano, M.1    Mackell, J.A.2    Ponton, M.3
  • 50
    • 0029613811 scopus 로고
    • The pharmacotherapy of Alzheimer's disease based on the cholinergic hypothesis: An update
    • (1995) Neurodegeneration , vol.4 , pp. 349-356
    • Weinstock, M.1
  • 51
    • 0034044642 scopus 로고    scopus 로고
    • Harmonization of dementia drug guidelines (United States and Europe): A report of The International Working Group for the Harmonization for Dementia Drug Guidelines
    • (2000) Alzheimer Dis Assoc Disord , vol.14 , Issue.SUPPL. 1
    • Whitehouse, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.