No linkage of the interleukin-4 receptor locus on chromosome 16p11.2-12.1 with sarcoidosis in German multiplex families

European Journal of Immunogenetics

Volumn 29, Issue 3, 2002, Pages 269-272

  Bohnert, A ^a   Schurmann M ^b,c   Hartung, A ^a   Hackstein, H ^a   Muller Quernheim J ^b,c   Bein, G ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c RESEARCH CENTER BORSTEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4 RECEPTOR; MICROSATELLITE DNA;

ALPHA CHAIN; ARTICLE; CHROMOSOME 16P; CONTROLLED STUDY; DNA FLANKING REGION; GENE FREQUENCY; GENE LOCUS; GENETIC LINKAGE; GENOTYPE; GERMANY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SARCOIDOSIS; SEGREGATION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMOSOME 16; CHROMOSOME MAP; GENETICS;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 16; GERMANY; HUMANS; LINKAGE (GENETICS); RECEPTORS, INTERLEUKIN-4; SARCOIDOSIS;

EID: 0036281467     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2370.2002.00291.x     Document Type: Article

References (23)

1. Th1/Th2 cell distribution in pulmonary sarcoidosis
2. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice
3. Biologic functions and signaling of the interleukin-4 receptor complexes
4. Definition of human interleukin-4 receptor alpha chain haplotypes and allelic association with atopy markers
5. The IL-4 receptor alpha-chain variant Q576R is strongly associated with decreased kidney allograft survival
6. Spontaneous production of various cytokines except IL-4 from CD4+ T cells in the affected organs of sarcoidosis patients
7. ATS/ERS/WASOG statement on sarcoidosis
8. Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily
9. Update on sarcoidosis
10. Association of interleukin-4 receptor and interleukin-4 promotor gene polymorphisms with systemic lupus erythematosus
11. Parametric and nonparametric linkage analysis: A unified multipoint approach
12. The polymorphisms S503P and Q576R in the interleukin-4 receptor alpha gene are associated with atopy and influence the signal transduction
13. Th1 and Th2 responses regulate experimental lung granuloma development
14. Angiotensin-converting enzyme gene polymorphism and risk of sarcoidosis
15. Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma
16. Involvement of T cells and alterations in T cell receptors in sarcoidosis
17. Generalization of the extended transmission disequilibrium test to two unlinked disease loci
18. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations
19. Transcriptional regulation of Th1/Th2 polarization
20. Familial sarcoidosis is linked to the major histocompatibility complex region
21. Sarcoidosis and common variable immunodeficiency. A case of a malignant course of sarcoidosis in conjunction with severe impairment of the cellular and humoral immune system
22. SLINK: A general simulation program for linkage analysis
23. Association of the interleukin-4 receptor α variant Q576R with Th1/Th2 imbalance in connective tissue disease