Coexistence of 21-hydroxylase and 11β-hydroxylase deficiency in adrenal incidentalomas and in subclinical cushing's syndrome

Hormone Research

Volumn 57, Issue 5-6, 2002, Pages 192-196

  Dall'Asta, Chiara ^a   Barbetta, Laura ^a   Libé, Rossella ^a   Passini, Elena ^a   Ambrosi, Bruno ^a,b,c  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

11 Hydroxylase; 21 Hydroxylase; Adrenal adenoma; Adrenal incidentaloma; Cushing's syndrome; Hypercortisolism

Indexed keywords

CORTICOTROPIN; CORTODOXONE; HYDROCORTISONE; HYDROXYPROGESTERONE; STEROID 11BETA MONOOXYGENASE; STEROID 21 MONOOXYGENASE;

ADRENAL CORTEX ADENOMA; ADULT; AGED; ARTICLE; COMORBIDITY; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; CORTICOTROPIN TEST; CUSHING DISEASE; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; FEMALE; HORMONE BLOOD LEVEL; HORMONE RELEASE; HORMONE RESPONSE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STEROID 11BETA MONOOXYGENASE DEFICIENCY;

17-ALPHA-HYDROXYPROGESTERONE; ADENOMA; ADRENAL GLAND NEOPLASMS; ADRENAL HYPERPLASIA, CONGENITAL; ADRENOCORTICOTROPIC HORMONE; ADULT; AGED; CORTODOXONE; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED;

EID: 0036278187     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000058381     Document Type: Article

References (19)

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2. Imaging of incidentally discovered adrenal masses
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4. Different patterns of steroid secretion in patients with adrenal incidentaloma
5. Impairment of 11β-hydroxylase but not 21-hydroxylase in adrenal incidentalomas
6. A survey on adrenal incidentaloma in Italy
7. Subclinical Cushing's syndrome in patients with adrenal incidentaloma: Clinical and biochemical features
8. Augmented 17-αhydroxyprogesterone response to ACTH stimulation as evidence of decreased 21-hydroxylase activity in patients with incidentally discovered adrenal tumours ('incidentaloma')
9. Apparent activities of 21-hydroxy-lase, 17α-hydroxylase and 17,20-lyase are impaired in adrenal incidentalomas
10. Comparative analysis of plasma 17-hydroxyprogesterone and cortisol responses to ACTH in patients with various adrenal tumors before and after unilateral adrenalectomy
11. Steroid response to ACTH in patients with an adrenal incidentaloma
12. Evidence of P450c11 hydroxylase deficiency in patients with incidentalomas
13. Steroid secretions in patients with adrenal incidentalomas
14. Impaired activity of 21-hydroxylase and 11β-hydroxylase in patients with adrenal incidentaloma
15. Expression of steroidogenic enzyme messenger ribonucleic acids and corticosteroid production in aldosterone-producing and 'nonfunctioning' adrenal adenomas
16. Management approaches to adrenal incidentalomas
17. No overrepresentation of congenital adrenal hyperplasia in patients with adrenocortical tumours
18. The adrenal hyperplasias
19. Intraadrenal steroid concentrations in man: Zonal differences and developmental changes