Hepatic glutaminase - A special role in urea synthesis?

Nutrition

Volumn 18, Issue 6, 2002, Pages 455-457

  Brosnan, John T ^a   Brosnan, Margaret E ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Ammonia; Carbamylphosphate synthetase; Glutamine; Insulin glucagons; Isotopomer; Liver perfusion; Metabolic channel; Mitochondria; N acetylglutamate

Indexed keywords

AMMONIA; ASPARTIC ACID; CARBAMOYL PHOSPHATE SYNTHASE; CITRULLINE; GLUCAGON; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; INSULIN; UREA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIVER PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT; UREA CYCLE;

AMMONIA; ANIMALS; CARBON-NITROGEN LIGASES; ENZYME INDUCTION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCAGON; GLUTAMINASE; LIVER; MITOCHONDRIA, LIVER; NITROGEN ISOTOPES; PERFUSION; RATS; UREA;

EID: 0036274433     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0899-9007(02)00776-1     Document Type: Article

References (11)

1. The synthesis of glutamine from glutamic acid and ammonia, and the enzymic hydrolysis of glutamine in animal tissues
2. A quantitative analysis of the control of glutamine catabolism in rat liver cells. Use of selective inhibitors
3. Hormonal control of hepatic glutaminase
4. Hepatic glutaminase expression; relationship to kidney-type glutaminase and to the urea cycle
5. Channeling of ammonia from glutaminase to carbamyl-phosphate synthetase in liver mitochondria
6. 15N-labelled ammonia in the perfused rat liver
7. 15N-labelled glutamine
8. Short term regulation of ureagenesis
9. The apparent Km of ammonia for carbamyl phosphate synthetase (ammonia) in situ
10. 15N] glutamine. Role of pH, hormones, and pyruvate