Regulation of [15N]urea synthesis from [5-15N]glutamine. Role of pH, hormones, and pyruvate

Journal of Biological Chemistry

Volumn 271, Issue 49, 1996, Pages 31234-31242

  Nissim, Itzhak ^a,c   Yudkoff, Marc ^a   Brosnan, John T ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; AMMONIUM CHLORIDE; ASPARTIC ACID; CITRULLINE; GLUCAGON; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; INSULIN; N ACETYLGLUTAMIC ACID; PYRUVIC ACID; TRACER; UREA; AMINO ACID; GLUTAMIC ACID DERIVATIVE; N-ACETYLGLUTAMATE;

AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; CELL ISOLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HORMONAL REGULATION; LIVER CELL; MALE; MASS SPECTROMETRY; METABOLIC REGULATION; NONHUMAN; PH; PRIORITY JOURNAL; RAT; UREA CYCLE; ANIMAL; LIVER; MASS FRAGMENTOGRAPHY; METABOLISM; SPRAGUE DAWLEY RAT;

AMINO ACIDS; AMMONIA; ANIMALS; CITRIC ACID CYCLE; CITRULLINE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCAGON; GLUTAMATES; GLUTAMINASE; GLUTAMINE; HYDROGEN-ION CONCENTRATION; INSULIN; LIVER; MALE; PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY; UREA;

EID: 0029658493     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.49.31234     Document Type: Article

References (50)

1. Halperin, M. L., Chen, C. B., Cheema-Dhadli, S., West, M. L., and Jungs, R. L. (1986) Am. J. Physiol. 250, F605-F612
2. Dodgson, S. J. (1987) Am. J. Physiol. 63, F2134-F2H1
3. Lund, P., and Wiggins, D. (1984) Biochem. J. 218, 991-994
4. Hensgens, H. E. S. J., Verhoeven, A. J., and Meijer, A. J. (1980) Eur. J. Biochem. 107, 197-204
5. Meijer, A. J., Lamers, W. H., and Chamuleau, R. A. F. M. (1990) Physiol. Rev. 70, 701-748
6. Bean, E. S., and Atkinson, D. E. (1984) J. Biol. Chem. 259, 1552-1559
7. Boon, L., Blommaart, P. J. E., Meijer, A. J., Lamers, W. H., and Schoolwerth, A. C. (1994) Am. J. Physiol. 267, F1015-F1020
8. Brosnan, J. T., Ewart, H. S., and Squires, S. A. (1995) Adv. Enzyme Regul. 35, 131-146
9. Nissim, I., Cattano, C., Nissim, I., and Yudkoff, M. (1992) Arch. Biochem. Biophys. 292, 393-401
10. Nissim, I., Cattano, C., Zhiping, L., and Nissim, I. (1993) J. Am. Soc. Nephrol. 3, 1416-1427
11. Haussinger, D. (1990) Biochem. J. 267, 281-290
12. Kashiwagura, T., Erecinska, M., and Wilson, D. F. (1985) J. Biol. Chem. 260, 407-414
13. McGivan, J. D., and Bradford, N. M. (1983) Biochem. Biophys. Acta 759, 296-303
14. Szweda, L. I., and Atkinson, D. E. (1989) J. Biol. Chem. 264, 15357-15360
15. Verhoeven, A. J., VanIwaarden, J. F., Joseph, S. K., and Meijer, A. J. (1983) Eur. J. Biochem. 133, 241-244
16. Exton, J. H. (1980) Am. J. Physiol. 238, E3-E12
17. Corvera, S., and Garcia-Sainz, A. (1983) Biochem. J. 210, 957-960
18. McGivan, J. D., Boon, K., and Doyle, F. A. (1991) Biochem. J. 274, 103-108
19. Garcia-Sainz, A., Hernandez-Sotomayor, T., Contreras-Rodrigues, J. L., and Macias-Silva, M. (1989) Biochem. Int. 18, 243-249
20. Meijer, A. J., Gimpel, J. A., Deleeuw, G., Tischler, M. E., Tager, J. M., and Williamson, J. R. (1978) J. Biol. Chem. 253, 2308-2320
21. Meijer, A. J. (1985) FEBS Lett. 191, 249-251
22. Nissim, I., States, B., Nissim, I., Zhi-Ping, L., and Yudkoff, M. (1995) Kidney Int. 47, 96-105
23. Brosnan, J. T., and Williamson, D. H. (1979) Biochem. J. 138, 453-462
24. Brosnan, J. T. (1982) Fed. Proc. 41, 91-95
25. Williamson, J. R., and Cooper, R. H. (1980) FEES Lett 117, 73-84
26. Martin-Requero, A., Cipres, G., Rodrigues, A., Ayuso, M. S., and Parrilla, R. (1992) Am. J. Physiol. 263, E493-E499
27. Hall, L. M., Metzenberg, R. L., and Cohen, P. P. (1958) J. Biol. Chem. 230, 1013-1021
28. Stewart, P. M., and Waiser, M. (1980) J. Biol. Chem. 256, 5270-5280
29. Tuchman, M., and Holzknecht, R. A. (1990) Pediat. Res. 27, 408-412
30. Kamemoto, E. S., and Atkinson, D. E. (1985) Arch. Biochem. Biophys. 243, 100-107
31. Cohen, N. S., and Cheung, C. W. (1984) Arch. Biochem. Biophys. 234, 31-44
32. Fahien, L. A., Schooler, J. M., Gehred, G. A., and Cohen, P. P. (1964) J. Biol. Chem. 239, 1935-1942
33. Blackmore, P. F., Assimacopoulos-Jeannet, F., Chan, T. M., and Exton, J. H. (1979) J. Bml. Chem. 254, 2828-2834
34. Hamberg, O., and Vilstrup, H. (1994) J. Hepatol. 21, 381-387
35. Almdal, T. P., Jensen, T., and Vilstrup, H. (1994) Metabolism 43, 328-332
36. Mariusz, K., Smogorzewski, M., Khilani, A., Michnowska, M., and Massry, S. (1994) Am, J. Physiol. 267, G754-G763
37. Nissim, I., Yudkoff, M., and Segal, S. (1985) J. Biol. Chem. 260, 13955-13967
38. Kun, E., and Kearney, E. B. (1974) in Methods of Enzymatic Analysis (Bergmeyer, H. U., ed) 2nd Ed., Vol. 4, pp. 1704-1708, Academic Press, New York
39. Brosnan, J. T., Brosnan, M. E., Charron, R., and Nissim, I. (1996) J. Biol. Chem. 271, 16199-16207
40. Wolfe, R. R. (ed) (1992) in Radioactive and Stable Isotope Tracers in Biomedicine: Principles and Practice of Kinetic Analysis, pp. 49-85, Wiley-Liss, New York
41. Nissim, I., Wehrli, W., States, B., Nissim, I., and Yudkoff, M. (1991) Biochem. J. 277, 33-38
42. Tuchman, M., and Holzknecht, R. A. (1990) Biochem. J. 271, 325-329
43. Vinay, P., Allignet, E., Pichette, C., Watford, M., Lemieux, G., and Gougoux, A. (1980) Kidney Int. 17, 312-325
44. Cooper, A. J. L, Nieves, E., Rosenspire, K. C., Filc-DeRicco, S., Gelbard, A. S., and Brusilow S. W.(1988) J. Biol. Chem. 263, 12268-12273
45. Cohen, N. S., Cheung, C.-W., and Raijman, L. (1980) J. Biol. Chem 255, 10248-10255
46. Cohen, N. S., Kyan, F. S., Kyan, S. S., Cheung, C. W., and Raijman, L. (1986) Biochem. J. 229, 205-211
47. McGivan, J. D., and Chappell, J. B. (1975) FEBS Lett. 52, 1-7
48. Lund, P., and Wiggins, D. (1986) Biochem. J. 239, 773-776
49. Cooper, A. J. L., and Anders, M. W. (1990) Ann. N. Y. Acad. Sci. 585, 118-127
50. Cyr, D. M., Egan, S. G., Brini, C. M., and Tremblay, G. C. (1991) Biochem. Pharmacol. 42, 645-655