Cardiac sodium and calcium channels: A history of excitatory currents

Cardiovascular Research

Volumn 55, Issue 1, 2002, Pages 1-8

  Fozzard, Harry A ^a  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CALCIUM CHANNEL; CALCIUM ION; ION CHANNEL; MARINE TOXIN; SODIUM CHANNEL; SODIUM ION;

ACTION POTENTIAL; BINDING AFFINITY; CALCIUM CURRENT; CALCIUM TRANSPORT; CHANNEL GATING; DEVELOPED COUNTRY; GENETIC DISORDER; HEART ARRHYTHMIA; HEART ATRIOVENTRICULAR NODE; HEART CONTRACTION; HEART DEATH; HEART MUSCLE CELL; HEART RHYTHM; HISTORY; HORMONE ACTION; HUMAN; ION TRANSPORT; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MEMBRANE TRANSPORT; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN MOTIF; REGULATORY MECHANISM; REVIEW; SINUS NODE; SODIUM CURRENT; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIA; HUMANS; ION CHANNEL GATING; ION CHANNELS; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; RESEARCH DESIGN;

EID: 0036269897     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00407-8     Document Type: Review

References (92)

1. + conduction and selectivity
2. Cellular electrophysiology of the heart
3. Electrical impedance of the squid giant axon during activity
4. Action potentials recorded from the inside a nerve fibre
5. The effect of sodium ions on the electrical activity of the giant axon of the squid
6. Measurements of current-voltage relations in the membrane of the giant axon of Loligo
7. A quantitative description of membrane current and its application to conduction and excitation in nerve
8. Potentiel de repos et potentiels d'action du muscle cardiaque, mesurés à l'aide d'électrodes intracellulaires
9. Cardiac resting and action potentials recorded with an intracellular electrode
10. Membrane resting and action potentials from single cardiac muscle fibers
11. The effect of the cardiac membrane potential on the rapid availability of the sodium-carrying system
12. Effect of current flow on the membrane potential of cardiac muscle
13. The effects of calcium ions and local anaesthetics on electrical properties of Purkinje fibres
14. Vagal and sympathetic effects on the pacemaker fibers in the sinus venosus of the heart
15. Voltage clamp technique in mammalian cardiac fibres
16. A modification of the Hodgkin-Huxley equations applicable to Purkinje fibre action and pace-maker potentials
17. Membrane capacity of the cardiac Purkinje fibre
18. Heart: Excitation and contraction
19. Sodium currents in single rat heart muscle cells
20. Open sodium channel properties of single canine cardiac Purkinje cells
21. Structure and function of voltage-gated sodium channels: Comparison of brain II and cardiac isoforms
22. Improved patch clamp techniques for high resolution current recording from cells and cell-free membrane patches
23. Single Na channel currents observed in cultured rat muscle cells
24. Sodium channels need not open before they inactivate
25. Sodium channels in cultured cardiac cells
26. Cardiac Na currents and the inactivity, reopening, and waiting properties of single cardiac Na channels
27. Kinetic analysis of single sodium channels from canine cardiac Purkinje cells
28. Charge movement associated with the opening and closing of the activation gate of the Na channels
29. A reinterpretation of mammalian sodium channel gating based on single channel recording
30. Two molecular transitions influence cardiac sodium channel gating
31. Nonlinear charge movement in mammalian cardiac ventricular cells. Components from Na and Ca channel gating
32. Gating currents associated with Na channels in canine cardiac Purkinje cells
33. Tetrodotoxin blockage of sodium conductance increase in lobster giant axons
34. Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes
35. Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin
36. Existence of distinct sodium channel messenger RNAs in rat brain
37. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence
38. + channel isoform
39. + channel isoform
40. Primary structure and expression of a sodium channel characteristic of denervated and immature rat skeletal muscle
41. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel
42. Molecular model of the action potential sodium channel
43. A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel-II
44. Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II
45. Calcium channel characteristics conferred on the sodium channel by single mutations
46. A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties
47. Molecular localization of an ion-binding site within the pore of mammalian sodium channels
48. + channel
49. SCN5A mutations associated with an inherited cardiac arrhythmia, the long QT syndrome
50. The electrical properties of crustacean muscle fibres
51. Differences in Na and Ca spikes as examined by application of tetrodotoxin, procaine, and manganese ions
52. Strom-spannungsbeziehungen von Purkinje-Fasern bei verscheidenen extracellulären Calcium-Konzentrationen und unter Adrenalineinwirkung
53. The dependence of slow inward current in Purkinje fibres on the extracellular calcium concentration
54. The voltage clamp and cardiac electrophysiology
55. Sodium/calcium exchange and control of calcium and contractility in cardiac and vascular smooth muscle
56. Die Calciumwirkung am Froshherzen als Funktion des Ionengleichgewichts zwischen Zellmembran und Umbegung
57. The antagonism between Ca and Na ions on the frog's heart
58. The dependence of calcium efflux from cardiac muscle on temperature and external ion composition
59. The influence of calcium on sodium efflux from intact squid giant axons
60. Increase in intracellular sodium acitivity during stimulation in mammalian cardiac muscle
61. The effects of membrane potential, extracellular potassium and tetrodotoxin on the intracellular sodium ion activity of sheep cardiac muscle
62. Membrane depolarization as a cause of tension development in mammalian ventricular muscle
63. Relationship between membrane voltage and tension in voltage-clamped cardiac Purkinje fibres
64. Effect of the duration of the action potential on contraction in the mammalian cardiac muscle
65. Relation between membrane potential, membrane currents, and activation of contraction in ventricular myocardial fibres
66. Slow inward current and contraction of sheep cardiac Purkinje fibers
67. Regenerative calcium release within muscle cells
68. Adrenaline-like effects of intracellular iontophoresis of cyclic AMP in cardiac Purkinje fibres
69. Membrane currents in rabbit sinoatrial node cells as studied by the double microelectrode method
70. Slow inward current and its role in mediating the chronotropic effect of epinephrine in the rabbit sino-artial node
71. Slow conduction in the atrioventricular node of the cat: A possible explanation
72. Effect of verapamil on the sinoatrial and atrioventricular nodes of the rabbit and the mechanism by which it arrests reentrant atrioventricular nodal tachycardia
73. Properties of single calcium channels in cardiac cell culture
74. A novel type of calcium channel in ventricular cells
75. Inactivation of Ca channels
76. Different modes of Ca channel gating behaviour favored by dihydropyridine Ca agonists and antagonists
77. β-adrenergic stimulation of calcium channels occurs by potentiation of high activity gating modes
78. Modulation of slow gating process of calcium channels by isoprenaline in guinea-pig ventricular cells
79. Two phosphatase sites on the Ca channel affecting different kinetic functions
80. Calcium antagonists and calcium agonists: Fundamental criteria and classification
81. Studies on Ca channels in intact cardiac cells: Voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers
82. 2+ current
83. Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules
84. Primary structure of the receptor for calcium channel blockers from skeletal muscle
85. Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel