Inhibitory effects of tramadol on nicotinic acetylcholine receptors in adrenal chromaffin cells and in Xenopus oocytes expressing α7 receptors

British Journal of Pharmacology

Volumn 136, Issue 2, 2002, Pages 207-216

  Shiraishi, Munehiro ^a   Minami, Kouichiro ^a   Uezono, Yasuhito ^b   Yanagihara, Nobuyuki ^a   Shigematsu, Akio ^a   Shibuya, Izumi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bovine adrenal chromaffin cells; Catecholamine secretion; Nicotinic acetylcholine receptors; Tramadol; Xenopus oocytes

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ALPHA BUNGAROTOXIN; CARBACHOL; CATECHOLAMINE; ION CHANNEL; NALOXONE; NICOTINE; NICOTINIC RECEPTOR; TRAMADOL; VERATRIDINE;

ANALGESIA; ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CATECHOLAMINE RELEASE; CATTLE; CHROMAFFIN CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONCENTRATION; MEMBRANE CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VOLTAGE CLAMP; XENOPUS;

ADRENAL MEDULLA; ANIMALS; CALCIUM; CATTLE; CELLS, CULTURED; CHROMAFFIN CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; OOCYTES; RECEPTORS, NICOTINIC; TRAMADOL; XENOPUS;

EID: 0036267449     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704703     Document Type: Article

References (48)

1. Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices
2. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors
3. gamma-Aminobutyric acid receptor channels in adrenal chromaffin cells: A patch-clamp study
4. Alpha-conotoxin ImI inhibits the alpha-bungarotoxin-resistant nicotinic response in bovine adrenal chromaffin cells
5. Neuronal nicotinic acetylcholine receptors on bovine chromaffin cells: Cloning, expression, and genomic organization of receptor subunits
6. Interaction of opiates with opioid binding sites in the bovine adrenal medulla: I. Interaction with delta and mu sites
7. Effect of activation of muscarinic receptors on intracellular free calcium and secretion in bovine adrenal chromaffin cells
8. Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes
9. Thiopental is a competitive inhibitor at the human alpha7 nicotinic acetylcholine receptor
10. Duality of the analgesic effect of tramadol in humans
11. The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex
12. Nicotinic receptor function: New perspectives from knockout mice
13. Primary structure of an agonist binding subunit of the nicotinic acetylcholine receptor from bovine adrenal chromaffin cells
14. Correlation of tramadol and M1 serum levels with antinociceptove activity in mice
15. alpha-Bungarotoxin-sensitive nicotinic receptors on bovine chromaffin cells: Molecular cloning, functional expression and alternative splicing of the alpha 7 subunit
16. Chronic nicotine exposure enhances cutaneous axon refexes in the rat
17. Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids
18. Recent studies of cutaneous nociception in atopic and non-atopic subjects
19. Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states
20. Allosteric modulations of the nicotinic acetylcholine receptor
21. Bioavailability of enteral tramadol formulations. 1st communication: Capsules
22. Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers
23. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits
24. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia
25. Mechanisms of sympathetic pain
26. + influx and muscarinic receptor-evoked cyclic GMP production in cultured bovine adrenal medullary cells
27. Modulation of neuronal nicotinic acetylcholine receptors by halothane in rat cortical neurons
28. Tramadol has no effect on cortical renal blood flow-despite increased serum catecholamine levels-in anesthetized rats: Implications for analgesia in renal insufficiency
29. The alpha-bungarotoxin site and its relation to the cholinergic and nerve growth factor mediated increases in tyrosine hydroxylase activity in cultures of sympathetic ganglia and chromaffin cells
30. Inhibition of spinal noradrenaline uptake in rats by the centrally acting analgesic tramadol
31. Nicotinic acetylcholine receptors on capsaicin-sensitive nerves
32. Nicotinic receptors in the development and modulation of CNS synapses
33. Tramadol inhibits norepinephrine transporter function at desipramine-binding sites in cultured bovine adrenal medullary cells
34. Halothane and isoflurane differentially affect the regulation of dopamine and gamma-aminobutyric acid release mediated by presynaptic acetylcholine receptors in the rat striatum
35. Ethanol inhibits the function of 5-hydroxytryptamine type 1c and muscarinic M1 G protein-linked receptors in Xenopus oocytes expressing brain mRNA: Role of protein kinase C
36. Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neurones
37. 1-like receptors
38. Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M1 receptors
39. Actions of cholinergic agonists and antagonists on sensory nerve endings in rat skin, in vitro
40. Characterization of the functional subunit combination of nicotinic acetylcholine receptors in bovine adrenal chromaffin cells
41. 3 and cAMP in bovine adrenal medullary cells
42. Preparation of barbiturate optical isomers and their effects on GABA(A) receptors
43. 45Ca influx and secretion ofcatecholamines in cultured bovine adrenal medulla cells
44. The chemical estimation of adrenaline-like substances in blood
45. Presynaptic nicotinic ACh receptors
46. Muscarinic receptor-mediated increase in cyclic GMP level in isolated bovine adrenal medullary cells
47. Halothane inhibits the cholinergic-receptor-mediated influx of calcium in primary culture of bovine adrenal medulla cells
48. Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems