In vitro biotransformation of sildenafil (Viagra) in the male rat: The role of CYP2C11

Drug Metabolism and Disposition

Volumn 30, Issue 6, 2002, Pages 655-657

  Warrington, Jill S ^a   Von Moltke, Lisa L ^a   Shader, Richard I ^a   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; CYTOCHROME P450 2C11; CYTOCHROME P450 2E1; CYTOCHROME P450 3A1; CYTOCHROME P450 3A2; DRUG METABOLITE; ENZYME ANTIBODY; SILDENAFIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; INCUBATION TIME; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; ISOENZYMES; MALE; MICROSOMES, LIVER; PIPERAZINES; PYRIMIDINONES; RATS; RATS, INBRED F344; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES;

ANIMALIA;

EID: 0036266176     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.6.655     Document Type: Article

References (16)

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