Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model

Annals of Thoracic Surgery

Volumn 73, Issue 6, 2002, Pages 1740-1746

  Fukunaga, Mari ^b   Takamori, Shinzo ^b   Hayashi, Akihiro ^b   Shirouzu, Kazuo ^b   Kosai, Ken Ichiro ^a  

^a GIFU UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GANCICLOVIR; THYMIDINE KINASE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CANCER SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; ISOGRAFT; LUNG CANCER; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; TRANSGENE; VIRUS INFECTION;

ADENOCARCINOMA; ADENOVIRIDAE; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; SIMPLEXVIRUS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0036263780     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(02)03572-5     Document Type: Article

References (15)

1. Lung cancer
2. Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: A 7-year assessment of a randomized controlled trial
3. Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
4. Combination suicide and cytokine gene therapy for hepatic metastasis of colon carcinoma: Sustained antitumor immunity prolongs animal survival
5. Gene therapy for hepatocellular carcinoma: Long-term remission of primary and metastatic tumors in mice by interleukin-2 gene therapy in vivo
6. Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
7. Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma
8. Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer
9. Combination gene therapy for liver metastasis of colon carcinoma in vivo
10. Gene therapy using adenovirus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer
11. Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene
12. Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice
13. Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice
14. Validation of an orthotopic model of human lung cancer with regional and systemic metastasis
15. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer