Reduction of hypoxia-inducible heme oxygenase-1 in the myocardium after left ventricular mechanical support

Journal of Pathology

Volumn 197, Issue 2, 2002, Pages 230-237

  Grabellus, Florian ^a   Schmid, Christof ^b   Levkau, Bodo ^b   Breukelmann, Dirk ^b   Halloran, Philip F ^c   August, Christian ^d   Takeda, Nobuakira ^e   Takeda, Atsushi ^f   Wilhelm, Markus ^b   Deng, Mario C ^b   Baba, Hideo A ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^e Jikei University Katsushika Medical Center   (Japan)

^f Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cell culture; Heme oxygenase 1; Hypoxia; Myocardium; Ventricular assist device

Indexed keywords

HEME OXYGENASE 1;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DEVICE; ENDOCARDIUM; ENZYME INDUCTION; EPICARDIUM; FEMALE; HEART ASSIST DEVICE; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIC HEART DISEASE; MALE; MYOCARDITIS; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; REDUCTION; STRESS;

ADULT; ANIMALS; ANOXIA; CELL HYPOXIA; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FEMALE; HEART FAILURE, CONGESTIVE; HEART-ASSIST DEVICES; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0036262210     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1106     Document Type: Article

References (26)

1. Weaning from mechanical cardiac support in patients with idiopathic dilated cardiomyopathy
2. Low incidence of myocardial recovery after left ventricular assist device implantation in patients with chronic heart failure
3. Bridging-to-recovery
4. Altered myocardial phenotype after mechanical support in human beings with advanced cardiomyopathy
5. Reversal of metallothionein expression is different throughout the human myocardium after prolonged left ventricular mechanical support
6. Regression of cellular hypertrophy after left ventricular assist device support
7. Myocardial gene expression of regulators of myocyte apoptosis and myocyte calcium homeostasis during hemodynamic unloading by ventricular assist devices in patients with end-stage heart failure
8. Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support: A potential mechanism for cardiac recovery
9. Myocytolysis (vacuolar degeneration) of myocardium: Immunohistochemical evidence of viability
10. The heme oxygenase system: A regulator of second messenger gases
11. Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells
12. Reduced stress defense in heme oxygenase 1-deficient cells
13. Chemical hypoxia triggers apoptosis of cultured neonatal rat cardiac myocytes: Modulation by calcium-regulated proteases and protein kinases
14. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure
15. Separate regulation of heme oxygenase and heat shock protein 70 mRNA expression in the rat heart by hemodynamic stress
16. Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells
17. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice
18. Improvement of myocardial mitochondrial function after hemodynamic support with left ventricular assist devices in patients with heart failure
19. Contrasting influences of alterations in ventricular preload and afterload upon systemic hemodynamics, function, and metabolism of ischemic myocardium
20. Ventricular filling pressure as a determinant of coronary blood flow during ischemia
21. Hemodynamics of collapsible vessel with tone: The vascular waterfall
22. Reversal of myocardial interleukin-6-mRNA expression following long-term left ventricular assist device support for myocarditis-associated low output syndrome
23. Reversible activation of nuclear factor-B in human end-stage heart failure after left ventricular mechanical support
24. Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues
25. Hypoxic stress induces cardiac myocyte-derived interleukin-6
26. Tissue expression and immunolocalization of tumor necrosis factor-alpha in postinfarction dysfunctional myocardium