Mechanism of suppression of insulin signalling with lignocaine

British Journal of Pharmacology

Volumn 136, Issue 1, 2002, Pages 76-80

  Hirose, Munetaka ^a   Martyn, J A Jeevendra ^b   Kuroda, Yoshihiro ^c   Marunaka, Yoshinori ^a   Tanaka, Yoshifumi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Insulin receptor; Lignocaine; Local anaesthetic; Phosphorylation; Skeletal muscle; Tyrosine kinase

Indexed keywords

ADENOSINE TRIPHOSPHATE; INSULIN; INSULIN RECEPTOR KINASE; INSULIN RECEPTOR SUBSTRATE 1; LIDOCAINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; RECEPTOR SUBTYPE; RECOMBINANT PROTEIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBUNIT; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TIBIALIS ANTERIOR MUSCLE;

ANESTHETICS, LOCAL; ANIMALS; DEPRESSION, CHEMICAL; INSULIN; LIDOCAINE; MALE; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; TYROSINE;

EID: 0036261345     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704691     Document Type: Article

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