Intron 3 16 bp duplication polymorphism of p53 is associated with an increased risk for breast cancer by the age of 50 years

Pharmacogenetics

Volumn 12, Issue 3, 2002, Pages 269-272

  Wang Gohrke, Shan ^a   Becher, Heiko ^a   Kreienberg, Rolf ^a   Runnebaum, Ingo B ^a   Chang Claude, Jenny ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Breast cancer; Genetic polymorphism; p53; Population based case control study; Risk factor

Indexed keywords

PROTEIN P53;

ADULT; AGE; ARTICLE; BREAST CARCINOGENESIS; CANCER RISK; CANCER SUSCEPTIBILITY; CONFIDENCE INTERVAL; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; GENE DUPLICATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENOTYPE; HUMAN; INTRON; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENE DUPLICATION; GENES, P53; GERMANY; HAPLOTYPES; HUMANS; INTRONS; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0036260271     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200204000-00012     Document Type: Article

References (10)

1. p53 polymorphism in ovarian and breast cancer
2. TP53 intron 6 polymorphism and the risk of ovarian and breast cancer
3. P53 germline polymorphisms are associated with an increased risk for breast cancer in German women
4. p53 polymorphisms and haplotypes in breast cancer
5. p53 haplotype determination in breast cancer
6. Breastfeeding and breast cancer risk by age 50 among women in Germany
7. Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations
8. A systematic review of genetic polymorphisms and breast cancer risk
9. Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer
10. True extended haplotypes of p53: Indicators of breast cancer risk