P53 germline polymorphisms are associated with an increased risk for breast cancer in German women

Anticancer Research

Volumn 18, Issue 3 B, 1998, Pages 2095-2099

  Wang Gohrke, Shan ^a   Rebbeck, Timothy R ^b   Besenfelder, Werner ^a   Kreienberg, Rolf ^a   Runnebaum, Ingo B ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer susceptibility; Genetic marker; Germline; Haplotype; Polymorphism

Indexed keywords

DNA; PROTEIN P53;

ADULT; ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; EXON; FEMALE; GERM LINE; GERMANY; HAPLOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; HUMAN CELL; INTRON; LEUKOCYTE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ADULT; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENES, P53; GERMANY; HAPLOTYPES; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK;

EID: 0031879598     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Coles, C, Condie, A, Chetty, U, Steel, CM, Evans, HJ, and Prosser, J: p53 mutations in breast cancer. Cancer Res 52: 5291-5298, 1992.
2. Runnebaum, IB, Nagarajan, M, Bowman, M, Soto, D, and Sukumar, S: Mutations in p53 as potential molecular markers for human breast cancer. Proc Natl Acad Sci U.S.A. 88: 10657-10661, 1991.
3. Harris, CC: p53: At the crossroads of molecular carcinogenesis and risk assessment. Science 262: 1980-1981, 1993.
4. Malkin, D, Li, FP, Strong, LC, Fraumeni, JJ, Nelson, CE, Kim, DH, Kassel, J, Gryka, MA, Bischoff, FZ, and Tainsky, MA: Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250: 1233-1238, 1990.
5. Hahn, M, Serth, J, Fislage, R, Wolfes, H, Allhoff, E, Jonas, V, and Pingoud, A: Polymerase chain reaction detection of a highly polymorphic VNTR segment in intron 1 of the human p53 gene. Clin Chem 39: 549-550, 1993.
6. Lazar, V, Hazard, F, Bertin, F, Janin, N, Bellet, D, and Bressac, B: Simple sequence repeat polymorphism within the p53 gene. Oncogene 8: 1703-1705, 1993.
7. Harris, N, Brill, E, Shohat, O, Prokocimer, M, Wolf, D, Arai, N, and Rotter, V: Molecular basis for heterogeneity of the human p53 protein. Mol Cell Biol 6: 4650-4656, 1986.
8. Matlashewski, GJ, Tuck, S, Pim, D, Lamb, P, Schneider, J, and Crawford, LV: Primary structure polymorphism at amino acid residue 72 of human p53. Mol Cell Biol 7: 961-963, 1987.
9. Peller, S, Kopilova, Y, Slutzki, S, Halevy, A, Kvitko, K, and Rotter, V: A novel polymorphism in intron 6 of the human p53 gene: a possible association with cancer predisposition and susceptibility. DNA Cell Biol 14: 983-990, 1995.
10. Carbone, D, Chiba, I, and Mitsudomi, T: Polymorphism at codon 213 within the p53 gene. Oncogene 6: 1691-1692, 1991.
11. Futreal, PA, Barrett, JC, and Wiseman, RW: An Alu polymorphism intragenic to the TP53 gene. Nucleic Acids Res 19: 6977, 1991.
12. Runnebaum, IB, Tong, XW, Konig, R, Zhao, H, Korner, K, Atkinson, EN, Kreienberg, R, and Kieback, DG: p53-based blood test for p55PIN3 and risk for sporadic ovarian cancer. Lancet 345: 1995.
13. Sjalander, A, Birgander, R, Athlin, L, Stenling, R, Rutegard, J, Beckman, L, and Beckman, G: P53 germ line haplotypes associated with increased risk for colorectal cancer. Carcinogenesis 16: 1461-1464, 1995.
14. Kawajiri, K, Nakachi, K, Imai, K, Watanabe, J, and Hayashi, S: Germ line polymorphisms of p53 and CYP1A1 genes involved in human lung cancer. Carcinogenesis 14: 1085-1089, 1993.
15. Sjalander, A, Birgander, R, Hallmans, G, Cajander, S, Lenner, P, Athlin, L, Beckman, G, and Beckman, L: p53 polymorphisms and haplotypes in breast cancer. Carcinogenesis 17: 1313-1316, 1996.
16. Birgander, R, Sjalander, A, Rannug, A, Alexandrie, AK, Sundberg, MI, Seidegard, J, Tornling, G, Beckman, G, and Beckman, L: P53 polymorphisms and haplotypes in lung cancer. Carcinogenesis 76: 2233-2236, 1995.
17. Birgander, R, Sjalander, A, Zhou, Z, Fan, C, Beckman, L, and Beckman, G: p53 polymorphisms and haplotypes in nasopharyngeal cancer. Hum Hered 46: 49-54, 1996.
18. Weston, A, Pan, CF, Ksieski, HB, Wallenstein, S, Berkowitz, GS, Tartter, PI, Bleiweiss, IJ, Brower, ST, Senie, RT, and Wolff, MS: p53 haplotype determination in breast cancer. Cancer Epidemiol Biomarkers Prev 6: 105-112, 1997.
19. Hill, WG: Estimation of linkage disequilibrium in randomly mating populations. Heredity 33: 229-239, 1974.
20. Terwilliger, JD, and Ott, J: Handbook of Genetic Linkage Analysis. Johns Hopkins University Press, Baltimore, 1994.
21. Birgander, R, Sjalander, A, Beckman, G, and Beckman, L: Effect of p53 alleles on placental weight . Hum Hered 46: 290-297, 1996.
22. Ambrosone, CB, Freudenheim, JL, Graham, S, Marshall, JR, Vena, JE, Brasure, JR, Laughlin, R, Nemoto, T, Michalek, AM, and Harrington, A: Cytochrome P4501A1 and glutathione S-transferase (M1) genetic polymorphisms and postmenopausal breast cancer risk. Cancer Res 55: 3483-3485, 1995.