Effect of albumin on phenytoin and tolbutamide metabolism in human liver microsomes: An impact more than protein binding

Drug Metabolism and Disposition

Volumn 30, Issue 6, 2002, Pages 648-654

  Tang, Cuyue ^a   Lin, Yuh ^a   Rodrigues, A David ^a   Lin, Jiunn H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPHENYTOIN; 4 HYDROXYTOLBUTAMIDE; ALBUMIN; BOVINE SERUM ALBUMIN; CYTOCHROME P450; PHENYTOIN; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCULATION; CATALYSIS; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG METABOLISM; ENZYME BINDING; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIVER MICROSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN METABOLISM; REACTION ANALYSIS;

HUMANS; MICROSOMES, LIVER; PHENYTOIN; PROTEIN BINDING; SERUM ALBUMIN, BOVINE; TOLBUTAMIDE;

BOVINAE;

EID: 0036259919     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.6.648     Document Type: Article

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