Comparing β-carotene, vitamin E and nitric oxide as membrane antioxidants

Biological Chemistry

Volumn 383, Issue 3-4, 2002, Pages 671-681

  Schafer, Freya Q ^a   Wang, Hong P ^a   Kelley, Eric E ^a   Cueno, Kate L ^a   Martin, Sean M ^a   Buettner, Garry R ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

carotene; Antioxidants; Free radicals; Lipid peroxidation; Nitric oxide; Singlet oxygen; Tocopherol; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BETA CAROTENE; FREE RADICAL; LIPID HYDROPEROXIDE; NITRIC OXIDE; OXYGEN; SINGLET OXYGEN; UNSATURATED FATTY ACID;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL PROTECTION; CHEMICAL REACTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NONHUMAN; OXIDATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; BETA CAROTENE; BIOLOGICAL TRANSPORT; CELL MEMBRANE PERMEABILITY; DIHEMATOPORPHYRIN ETHER; HL-60 CELLS; HUMANS; K562 CELLS; LEUKEMIA L1210; LIGHT; MICE; NITRIC OXIDE; TUMOR CELLS, CULTURED; VITAMIN E;

ANIMALIA;

EID: 0036254707     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2002.069     Document Type: Article

References (46)

1. Nonantioxidant functions of α-to-copherol in smooth muscle cells
2. Quantitative Studies of peroxidation, antioxidant action, partitioning, and oxidative stress
3. Reaction of ascorbate with the α-tocopheroxyl radical in micellar and bilayer membrane systems
4. Uptake of hematoporphyrin derivative by normal and malignant cells: Effect of serum, pH, temperature, and cell size
5. Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant
6. The pecking order of free radicals and antioxidants: Lipid peroxidation, α-tocopherol, and ascorbate
7. Membrane lipid free radicals produced from L1210 murine leukemia cells by Photofrin® photosensitization: An EPR spin trapping study
8. Is vitamin E the only lipid soluble, chain breaking antioxidant in human blood plasma and erythrocyte membranes?
9. Regeneration of vitamin E in human platelets
10. Vitamin E and oxidative stress
11. The kinetics of the autoxidation polyunsaturated fatty acids
12. Effect of oral supplementation with D-α-to-copherol on the vitamin E content of human low density lipoproteins and resistance to oxidation
13. Continuous monitoring of in vitro oxidation of human low density lipoprotein
14. Chemistry of singlet oxygen: VIII quenching by β-carotene
15. Oxygen radical chemistry of polyunsaturated fatty acids
16. Carotenoids as scavengers of active oxygen species
17. Lipid peroxidation and endothelial cell injury: Implications in atherosclerosis
18. Relative α-to-copherol deficiency in cultured tumor cells: Free radical-mediated lipid peroxidation, lipid oxidizability, and cellular polyunsaturated fatty acid content
19. Nitric oxide inhibits iron-induced lipid peroxidation in HL-60 cells
20. The role of nitric oxide in the response of cancerous lesions to photodynamic therapy
21. Relevance of nitric oxide to the response of tumors to photodynamic therapy
22. Selenoperoxidase-mediated cytoprotection against merocyanine 540-sensitized photoperoxidation and photokilling of leukemia cells
23. Protective effect of β-carotene against lethal photosensitization by hematoporphyrin
24. β-Carotene as a photoprotective agent in erythropoietic protoporphyria
25. Antioxidants in relation to lipid peroxidation
26. Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C
27. Nitric oxide inhibition of lipid peroxidation: Kinetics of reaction with lipid peroxylradicals and comparison with α-tocopherol
28. The reaction of nitric oxide with organic peroxyl radicals
29. Mechanism of free radical oxidation of unsaturated unsaturated lipids
30. EPR detection of lipid-derived free radicals from PUFA, LDL, and cell oxidations
31. Acidic pH amplifies iron-mediated lipid peroxidation in cells
32. Interaction of vitamin C and vitamin E during free radical stress in plasma: An ESR study
33. Biology of a photosynthetic bacterium which lacks colored carotenoids
34. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
35. Role of lipid peroxidation in hematoporphyrin derivative-sensitized photokilling of tumor cells: Protective effects of glutathione peroxidase
36. Singlet oxygen intermediacy in the photodynamic action of membrane-bound hematoporphyrin derivative
37. Cosupplementation with coenzyme Q prevents the prooxidant effect of alpha-tocopherol and increases the resistance of LDL to transition metal-dependent oxidation initiation
38. Nitric oxide synthase activity in human breast cancer
39. Standardization of nitric oxide solutions using an oxygen monitor
40. Free radical-mediated lipid peroxidation in cells: Oxidizability is a function of cell lipid bis-allylic hydrogen content
41. Vitamin E slows the rate and delays the onset of free radical-mediated lipid peroxidation in cells
42. Radical-initiated lipid peroxidation in low density lipoproteins: Insights obtained from kinetic modeling
43. Phospholipid hydroperoxide glutathione peroxidase protects against singlet oxygen-induced cell damage
44. Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: A key step in hydroperoxide-amplified lipid peroxidation
45. Rate constants for the decay and reactions of the lowest electronically excited singlet state of molecular oxygen in solution
46. Role of α-tocopheroxyl radical in the initiation of lipid peroxidation in human low-density lipoprotein exposed to horseradish peroxidase