Relationship between chromatographic behavior and affinity to 5-HT1A serotonin receptors of new buspirone analogues

Journal of Separation Science

Volumn 25, Issue 5-6, 2002, Pages 273-279

  Nasal, Antoni ^a   Wojdełko, Anna ^a   Baczek, Tomasz ^a   Kaliszan, Roman ^a   Cybulski, Marcin ^b   Chilmonczyk, Zdzisław ^c,d  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE   (Poland)

^c NATIONAL MEDICINES INSTITUTE   (Poland)

^d UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

5 HT1A serotonin receptors; Buspirone analogues; Chemometrics; High performance liquid chromatography (HPLC); Principal component analysis (PCA)

Indexed keywords

BIOASSAY; COMPUTATIONAL METHODS; DATA PROCESSING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRINCIPAL COMPONENT ANALYSIS;

DRUG ANALYTES;

DRUG PRODUCTS;

BUSPIRONE; BUSPIRONE DERIVATIVE; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHEMOMETRIC ANALYSIS; CHROMATOGRAPHY; COMPARATIVE STUDY; COMPUTER ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CLASSIFICATION; DRUG DETERMINATION; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG RETENTION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; INFORMATION PROCESSING; MULTIVARIATE ANALYSIS; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PHYSICAL CHEMISTRY; PRINCIPAL COMPONENT ANALYSIS; RAT; STATISTICAL ANALYSIS; TRANQUILIZING ACTIVITY;

ANIMALIA;

EID: 0036254675     PISSN: 16159306     EISSN: None     Source Type: Journal    
DOI: 10.1002/1615-9314(20020401)25:5/6<273::AID-JSSC273>3.0.CO;2-5     Document Type: Article

References (30)