Conformational flexibility of serotonin(1A) receptor ligands from crystallographic data. Updated model of the receptor pharmacophore

Archiv der Pharmazie

Volumn 330, Issue 5, 1997, Pages 146-160

  Chilmonczyk, Zdzisław ^a   Szelejewska Wozniakowska, Agnieszka ^a   Cybulski, Jacek ^a   Cybulski, Marcin ^a   Kozioł, Anna E ^b   Gdaniec, Maria ^c  

^a INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE   (Poland)

^b MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^c ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

Anxiety; Conformational analysis; Crystal structure; Serotonin receptors

Indexed keywords

BUSPIRONE; BUSPIRONE DERIVATIVE; GEPIRONE; LIGAND; MEPROBAMATE; RITANSERIN; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; TANDOSPIRONE; UNCLASSIFIED DRUG; WY 48 723 2; SEROTONIN 1 RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR;

ANXIETY NEUROSIS; ARTICLE; CRYSTAL STRUCTURE; DEPRESSION; DRUG CONFORMATION; DRUG RECEPTOR BINDING; PRIORITY JOURNAL; RECEPTOR AFFINITY; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION; TRANQUILIZING ACTIVITY; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CRYSTALLOGRAPHY; METABOLISM; RADIOASSAY; RAT;

ANIMALS; BINDING SITES; BUSPIRONE; CRYSTALLOGRAPHY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RADIOLIGAND ASSAY; RATS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030611962     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19973300507     Document Type: Article

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