Stimulation of arginine consumption and asparagine production in LPS-activated macrophages

Anticancer Research

Volumn 22, Issue 1 A, 2002, Pages 203-209

  Suzuki, Fumika ^a   Tashiro, Miyuki ^a   Hashimoto, Ken ^a   Yokote, Yoshiko ^a   Akahane, Kiso ^a   Sakagami, Hiroshi ^a  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Asparagine production; LPS; Macrophage; NO

Indexed keywords

ARGININE; ASPARAGINE; BIOLOGICAL MARKER; CITRULLINE; GLUTAMINE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; SERINE; TRICHLOROACETIC ACID;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ARGININE; ASPARAGINE; CELLS, CULTURED; GLUTAMINE; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; STIMULATION, CHEMICAL;

EID: 0036253742     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. (-) epigallocatechin-3:gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-κB
2. Changes in intracellular concentration of amino acids and polyamine during apoptosis of HL-60 cells
3. Changes in amino acid pool and utilization during the apoptosis of HL-60 cells induced by epigallocatechin gallate or gallic acid
4. Effects of prenylflavanones from Sophora species on growth and activation of mouse macrophage-like cell line
5. Carboxypeptidase D is up-regulated in Raw 264.7 macrophages and stimulates nitric oxide synthesis by cells in arginine-free medium
6. Up-regulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS
7. Sustained nitric oxide production in macrophages requires the arginine transporter CAT 2
8. Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide
9. Nitric oxide up-regulates DNA-binding activity of nuclear factor-kappaB in macrophages stimulated with silica and inflammatory stimulants
10. Decrease in asparagine synthetase activity during cell differentation of mouse and human leukemic cell lines
11. Characterization of high molecular weight glucosylated forms of murine tumor necrosis factor
12. Lipid A related compounds XXIX. Synthesis of biologically active N-acylated L-asparagine-containing D-glucosamine derivatives structurally related to lipid A