The NH2-terminal propeptides of fibrillar collagens: Highly conserved domains with poorly understood functions

Matrix Biology

Volumn 21, Issue 3, 2002, Pages 217-226

  Bornstein, Paul ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cysteine rich repeats; Exon 2 deleted mouse; N propeptide; Type I procollagen

Indexed keywords

AMINE; AMINO ACID; COLLAGEN; CYSTEINE; PEPTIDE; PROCOLLAGEN;

AMINO ACID SEQUENCE; AMPHIBIA; ARTICLE; BIOGENESIS; BIRD; BREEDING; EXON; FISH; GENE DELETION; GENETIC CODE; HETEROZYGOSITY; IN VITRO STUDY; MAMMAL; MOUSE MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; RODENT; SEQUENCE ANALYSIS; SPECIES DIFFERENCE; STRUCTURE ANALYSIS; VERTEBRATE;

AMPHIBIA; AVES; MAMMALIA; RODENTIA; VERTEBRATA;

EID: 0036253136     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(02)00008-2     Document Type: Review

References (67)

1. Evidence for procollagen, a biosynthetic precursor of collagen
2. Nucleotide sequence of pre-pro-von Willebrand factor cDNA
3. The biosynthesis of collagen
4. The thrombospondins: Structure and regulation of expression
5. The chemistry and biology of collagen
6. The amino acid sequence encoded by exon 2 of the murine collal gene is not required for normal secretion, processing by procollagen N-proteinase or fibrillogenesis of type I collagen in mice
7. Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagen
8. Components of increased labelling with putrescine and fucose during healing of skin wounds
9. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
10. Complete amino acid sequence of the N-terminal extension of calf skin type III collagen
11. Three conformationally distinct domains in the amino-terminal segment of type III procollagen and its rapid triple helix to coil transition
12. CDNA cloning and expression of bovine procollagen I N-proteinase: A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components
13. Human Ehlers-Danlos syndrome type VIIC and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene
14. The establishment of Spemann's organizer and patterning of the vertebrate embryo
15. A common plan for dorsoventral patterning in Bilateria
16. Folding of carboxyl domain and assembly of procollagen I
17. Physical properties of the amino-terminal precursor-specific portion of type I procollagen
18. Genomic sequence of mouse COL1A1 encoding the collagen propeptides
19. Procollagen intermediates during tendon fibrillogenesis
20. Ultrastructural identification of extension aminopropeptides of type I and type III collagens in human skin
21. Feedback regulation of collagen gene expression: A Trojan horse approach
22. Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation
23. Structural organization of distinct domains within the non-collagenous N-terminal region of collagen type XI
24. Characterization of type I procollagen N-proteinase from fetal bovine tendon and skin: Purification of the 500-kilodalton form of the enzyme from bovine tendon
25. The Xenopus dorsalizing factor noggin ventralized Drosophila embryos by preventing DPP from activating its receptor
26. Regulation of protein synthesis: Translational control by procollagen-derived fragments
27. Endoplasmic reticulum protein Hsp47 binds specifically to the N-terminal globular domain of the amino-propeptide of the procollagen I α1(I)-chain
28. Inhibition of angiogenesis by thrombospondin-1 is mediated by two independent regions within the type I repeats
29. Further evidence for a transport form of collagen: Its extrusion and extracellular conversion to tropocollagen in embryonic tendon
30. Role of thrombospondin-1-derived peptide, 4N1K, in FGF-2-induced angiogenesis
31. Amino-terminal extension peptides from type I procollagen normalize excessive collagen synthesis of scleroderma fibroblasts
32. Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2
33. BMP-binding modules in chordin: A model for signalling regulation in the extracellular space
34. The CCN family of angiogenic regulators: The integrin connection
35. The nature of the collagen synthesized by cultured human fibroblasts
36. Deletion of the pro-alpha1(I) N-propeptide affects secretion of type-I collagen in Chinese hamster lung cells but not in Mov-13 mouse cells
37. Identification of the molecular recognition sequence which determines the type-specific assembly of procollagen
38. Collagen made of extended α-chains, procollagen, in genetically-defective dermatosparaxic calves
39. Tissue-specific and differential expression of alternatively spliced alpha 1 (II) collagen mRNAS in early human embryos
40. The role of collagen-derived proteolytic fragments in angiogenesis
41. Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins
42. Procollagen
43. Molecular recognition in procollagen chain assembly
44. Physical characterization of the procollagen module of human thrombospondin 1 expressed in insect cells
45. Type IIA procollagen: Expression in developing chicken limb cartilage and human osteoarthritic articular cartilage
46. Peroxidasin: A novel enzyme-matrix protein of Drosophila development
47. Preferential expression of alternatively spliced messenger RNAs encoding type-II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and non-chondrogenic tissues during early mouse development
48. Production of human type I collagen in yeast reveals unexpected new insights into the molecular assembly of collagen trimers
49. Inhibition of procollagen cell-free synthesis by amino-terminal extension peptides
50. Cleavage of chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity
51. Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
52. Collagens: Molecular biology, diseases and potentials for therapy
53. Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling
54. Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA
55. The human type II procollagen gene: Identification of an additional protein-coding domain and location of potential regulatory sequences in the promoter and first intron
56. Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: Differential expression of the amino-propeptide
57. Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non-cartilaginous tissues during early mouse development
58. Electronoptical studies of procollagen from the skin of dermatosparaxic calves
59. Organization of the exons coding for pro α1(II) collagen N-propeptide confirms a distinct evolutionary history of this domain of the fibrillar collagen genes
60. Complete structural organization of the human α1(V) collagen gene (COL5A1): Divergence from the conserved organization of other characterized fibrillar collagen genes
61. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
62. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity
63. Biosynthetic processing of the pro-α1(V)2pro-α2(V) collagen heterotrimer by bone morphogenetic protein-1 and furin-like proprotein convertases
64. Inhibiting effect of procollagen peptides on collagen biosynthesis in fibroblast cultures
65. 2-propeptide by enzymic processing reveals a unique developmental pathway
66. Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-β1 and BMP-2