Cre-loxP recombination system for large genome rearrangements in Lactococcus lactis

Applied and Environmental Microbiology

Volumn 68, Issue 5, 2002, Pages 2359-2367

  Campo, Nathalie ^a   Daveran Mingot, Marie Line ^a   Leenhouts, Kees ^a   Ritzenthaler, Paul ^a   Le Bourgeois, Pascal ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GENES; GENETIC ENGINEERING; MODIFICATION;

HOMOLOGOUS RECOMBINATION;

BACTERIA;

CRE RECOMBINASE;

BACTERIUM; GENOME;

ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL GENOME; CHROMOSOME INVERSION; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA TRANSPOSITION; GENETIC RECOMBINATION; GENOME ANALYSIS; GRAM POSITIVE BACTERIUM; HOMOLOGOUS RECOMBINATION; LACTOCOCCUS LACTIS; LOXP GENE; NONHUMAN;

CHROMOSOMES, BACTERIAL; CULTURE MEDIA; GENE REARRANGEMENT; GENOME, BACTERIAL; INVERSION, CHROMOSOME; LACTOCOCCUS LACTIS; MOLECULAR WEIGHT; RECOMBINATION, GENETIC;

BACTERIA (MICROORGANISMS); LACTOCOCCUS; LACTOCOCCUS LACTIS; POSIBACTERIA; PROKARYOTA; STREPTOCOCCUS;

EID: 0036250274     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.68.5.2359-2367.2002     Document Type: Article

References (42)

1. Studies on the properties of P1 site-specific recombination: Evidence for topologically unlinked products following recombination
2. A recombinase-based selection of differentially expressed bacterial genes
3. Altered directionality in the Cre-loxP site-specific recombination pathway
4. High-frequency Flp recombinase inversions of the oriC-containing region of the Pseudomonas aeruginosa genome
5. The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403
6. Recombination within the yeast plasmid 2μ circle is site-specific
7. The diverse and dynamic structure of bacterial genomes
8. Insertion and amplification of foreign genes in the Lactococcus lactis subsp. lactis chromosome
9. Construction and evaluation of new drug-resistance cassettes for gene disruption mutagenesis in Streptococcus pneumoniae, using an ami test plaform
10. Genomic organization of lactic acid bacteria
11. Functional analysis of promoters in the nisin gene cluster of Lactococcus lactis
12. Plasmid complements of Streptococcus lactis NCDO712 and other lactic streptococci after protoplast-induced curing
13. Comparative genomics of Listeria species
14. - plasmids and their in vivo chromosomal integration and retrieval
15. Effects on chromosomal inversion on cell fitness in Escherichia coli K-12
16. A bacterial model system for chromosomal targeting
17. Strain-specific genes of Helicobacter pylori: Distribution, function and dynamics
18. Site-specific recombinases: Tools for genome engineering
19. Recombination by replication
20. Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity
21. Quorum sensingcontrolled gene expression in lactic acid bacteria
22. Cloning and nucleotide base sequence analysis of a spectinomycin adenyltransferase AAD(9) determinant from Enterococcus faecalis
23. Genome plasticity among related Lactococcus strains: Identification of genetic events associated with macrorestriction polymorphisms
24. Electrotransformation of Lactococcus lactis
25. New tools for the physical and genetic mapping of Lactococcus strains
26. Physical and genetic map of the Lactococcus lactis subsp. cremoris MG1363 chromosome: Comparison with that of Lactococcus lactis subsp. lactis IL1403 reveals a large genome inversion
27. Construction of a food-grade multiple-copy integration system for Lactococcus lactis
28. A general system for generating unlabelled gene replacements in bacterial chromosomes
29. Campbell-like integration of heterologous plasmid DNA into the chromosome of Lactococcus lactis subsp. lactis
30. Characterization and properties of very large inversions of the E. coli chromosome along the origin-to-terminus axis
31. Efficient insertional mutagenesis in lactococci and other gram-positive bacteria
32. Constitutive expression of erythromycin resistance mediated by the ermAM determinant of plasmid pAMβ1 results from deletion of 5′ leader peptide sequences
33. Detection and possible role of two large nondivisible zones on the Escherichia coli chromosome
34. Universal replication biases in bacteria
35. Rearrangement of the bacterial chromosome: Forbidden inversions
36. Approaches to half-tetrad analysis in bacteria: Recombination between repeated, inverse-order chromosomal sequences
37. Cloning of chromosomal genes in Streptococcus pneumoniae
38. Improved medium for lactic streptococci and their bacteriophages
39. A method to invert DNA segments of the Bacillus subtilis 168 genome by recombination between homologous sequences
40. Isolation and characterization of Streptococcus cremoris Wg2-specific promoters
41. Cre/loxP-mediated excision and amplification of large segments of the Escherichia coli genome
42. Engineering mouse chromosomes with Cre-loxP: Range, efficiency, and somatic applications