Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: A microdialysis study

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 365, Issue 5, 2002, Pages 378-387

  Míguez, Jesús M ^a,b   Paz Valiñas, Lucinda ^a,b   Míguez, Isabel ^a,b   Aldegunde, Manuel ^a,b  

^a UNIVERSITY OF VIGO   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

In vivo microdialysis; Median raphe; Paroxetine; Pindolol; Serotonin release; Somatodendritic autoreceptors; Ventral hippocampus

Indexed keywords

AUTORECEPTOR; PAROXETINE; PINDOLOL; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN PERFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG INFUSION; HIPPOCAMPUS; INNERVATION; MALE; MEDIAN RAPHE NUCLEUS; MICRODIALYSIS; NONHUMAN; PERIKARYON; PRESYNAPTIC NERVE; RACEMIC MIXTURE; RAT; RECEPTOR BLOCKING; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; AUTORECEPTORS; DENDRITES; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; HYDROXYINDOLEACETIC ACID; MALE; MICRODIALYSIS; PAROXETINE; PINDOLOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; STEREOISOMERISM; SYNAPTIC TRANSMISSION;

EID: 0036245402     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-002-0530-5     Document Type: Article

References (54)

1. Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytrytamine in raphe nuclei and frontal cortex. An in vivo microdialysis study
2. In vivo dialysis study of the somatodendritic release of serotonin in the raphe nuclei of the rat: Effects of 8-hydroxy-2-(di-n-propylamino)tetralin
3. 1A receptors in the human brain confirmed with positron emission tomography
4. 1A receptor antagonists increase the activity of serotonergic cells in the dorsal raphe nucleus in rats treated acutely or chronically with citalopram
5. 1A receptor agonist properties of (-)pindolol in combination with citalopram on serotonergic dorsal raphe cell firing in vivo
6. Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors
7. 1A antagonists
8. How does pindolol improve antidepressant action?
9. Therapeutic effects of serotonin uptake inhibitors in depression
10. Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the raphe nuclei: An in vivo microdialysis study
11. Effectiveness of pindolol with selected antidepressant drugs in the treatment of major depression
12. Role of somatodendritic 5-HT autoreceptors in modulating 5-HT neurotransmission
13. 1A receptors in augmenting antidepressant activity in the mouse swimming test
14. Affinity of (±)-pindolol, (-)-penbutolol, and (-)-tertatolol for pre- and postsynaptic serotonin 5-HT1A receptors in human and rat brain
15. 1A autoreceptor in vivo
16. 1A receptors in the rat brain
17. The role of 5-HT(1A) and 5-HT(1B) receptors on the modulation of acute fluoxetine-induced changes in extracellular 5-HT: The mechanism of action of (±)-pindolol
18. 1A receptors
19. 1A receptors potentiates the increases in extracellular monoamines induced by du-loxetine in hypothalamus
20. Pindolol suppresses serotonergic neuronal activity and does not block the inhibition of serotonergic neurons produced by 8-hydroxy-2-(di-n-propylamino)tetralin in awake cats
21. Pindolol increases extracellular 5-HT while inhibiting serotonergic neuronal activity
22. Short-term fluoxetine treatment alters monoamine levels and turnover in discrete brain nuclei
23. Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: Effects on 5-HT cell firing and extracellular 5-HT
24. Effects of (-)-tertatolol, (-)-penbutolol and (±)-pindolol in combination with paroxetine on presynaptic 5-HT function: An in vivo microdialysis and electrophysiological study
25. 1B receptors
26. 1B receptors with WAY 100,635 and GR 127,935
27. Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine
28. Effect of fluoxetine on extracellular 5-hydroxytryptamine in rat brain. Role of autoreceptors
29. 1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: A microdialysis study
30. (-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine
31. 1A receptors or β-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo
32. 3H]imipramine localization and relationship to serotonin transporter
33. Hippocampal 5-HT synthesis and release in vivo is decrease by infusion of 8-OH-DPAT into the nucleus raphe dorsalis
34. Administration of 8-hydroxy-2-(di-n-propylamino)tetralin in raphe nuclei dorsalis and medianus reduces serotonin synthesis in rat brain: Differences in potency and regional sensitivity
35. 1A receptor antagonist on citalopram-induced increase in extracellular serotonin in the frontal cortex, striatum and dorsal hippocampus
36. A stereotaxic atlas of the forebrain and lower parts of the brain stem
37. Age dependent β-adrenergic response of neuronal discharge in the raphe dorsalis: Evidence of a transient regulation
38. 1B receptors
39. 11C)WAY 100635 and positron emission tomography in humans
40. Serotonin (5-HT) release in the dorsal raphé and ventral hippocampus: Raphé control of somatodendritic and terminal 5-HT release
41. Functional mapping of dorsal and medial raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis
42. (-)-Pindolol increases dialysate concentrations of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely-moving rats
43. The serotonergic and noradrenergic systems of the hippocampus: Their interactions and the effects of antidepressants treatments
44. Effects of milnacipram and pindolol on extracellular noradrenaline and serotonin levels in guinea pig hypothalamus
45. 1A) receptors
46. 1A) receptor-mediated modulation of adenylate cyclase activity by pindolol and propanolol isomers
47. Displacement of the binding of 5-HT(1A) receptor ligand to pre- and postsynaptic receptors by (-)-pindolol. A comparative study in rodent, primate and human brain
48. 1A receptor antagonists in the dorsal raphe pathway. Role of somatodendritic autoreceptors
49. 1A receptors. In vivo microdialysis and electrophysiological studies in the rat brain
50. Acute uptake inhibition increases extracellular serotonin in the rat forebrain
51. Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis
52. 1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo
53. Pindolol potentiates the effect of fluoxetine on hippocampal seizures of rats
54. Faster onset of action of fluvoxamine in combination with pindolol in the treatment of delusional depression: A controlled study