T type 1/type 2 subsets balance in B-cell chronic lymphocytic leukemia - The three-color flow cytometry analysis

Leukemia Research

Volumn 26, Issue 7, 2002, Pages 657-660

  Podhorecka, Monika ^a   Dmoszynska, Anna ^a   Rolinski, Jacek ^a   Wasik, Ewa ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

B CLL; Flow cytometry; IFN ; IL 4; T type 1 T type 2

Indexed keywords

ARTICLE; B LYMPHOCYTE; BIOACCUMULATION; BLOOD; CELL FUNCTION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; EVALUATION; FLOW CYTOMETRY; HUMAN; IMMUNE DEFICIENCY; IMMUNE SYSTEM; IMMUNITY; IMMUNOCOMPETENT CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TECHNIQUE; TH1 CELL; TH2 CELL;

ANTIGENS, CD3; ANTIGENS, CD8; BIOLOGICAL MARKERS; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; DISEASE PROGRESSION; FLOW CYTOMETRY; HUMANS; IMMUNITY, CELLULAR; INTERFERON TYPE II; INTERLEUKIN-4; LEUKEMIA, B-CELL, CHRONIC; TH1 CELLS; TH2 CELLS;

EID: 0036242830     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(01)00194-1     Document Type: Article

References (8)

1. Lung carcinoma: Analysis of T helper type 1 and type 2 cells and T cytotoxic type 1 and type 2 cells by intracellular cytokine detection with flow cytometry
2. Type 1 and type 2 cyokine dysregulation in human infectious neoplastic and inflammatory diseases
3. B-Cell chronic lymphocytic leukemia: A bird of a different feather
4. CD57+/CD28- T cells in untreated hemato-oncological patients are expanded, CD57+/CD28- T cells in untreated hemato-oncological patients are expanded and display a Th1-type cytokine secretion profile
5. Reduced IL-4 and INF gamma expression by CD4 T cells in patients with chronic lymphocytic leukaemia
6. IL-4 production and increased CD30 expression by a unique CD8+ T cell subset in B cell chronic lymphocytic leukaemia
7. Analysis of blood T cell cytokine expression in B-chronic lymphocytic leukaemia: Evidence for increased levels of cytoplasmic IL-4 in resting and activated CD8 T cells.