Synthesis and bronchodilatory activity of some nitrogen bridgehead compounds

European Journal of Medicinal Chemistry

Volumn 37, Issue 5, 2002, Pages 419-425

  Jindal, Dharam Paul ^a   Bhatti, Ravinder Singh ^a   Ahlawat, Seema ^a   Gupta, Ranju ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Bronchodilators; Guinea pig tracheal chains; Nitrogen bridgehead compounds; Quinazoline; Theophylline; Vasaka alkaloids

Indexed keywords

2,3,4,5 TETRAHYDROAZEPINO[2,1 B] 8,9 DIMETHOXYQUINAZOLIN 11(1H) ONE; 9 (2 PICOLYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (3 INDOLYLMETHYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (3',4' DIMETHOXYBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (3',4',5' TRIMETHOXYBENZAMIDO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (3',4',5' TRIMETHOXYBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (4 PICOLYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (4' CYANOBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (4' ISOPROPYLBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (4' METHOXYBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (4' NITROBENZYLAMINO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (5',6' DIMETHOXYPHTHALIMIDO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 (DIMETHYLACETAMIDO) 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; 9 AMINO 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 1(1H) ONE; 9 AMINO 2,3,4,5 TETRAHYDROAZEPINO[2,1 B]QUINAZOLIN 11(1H) ONE; AMINOPHYLLINE; BRONCHODILATING AGENT; DPJ 386; FUNCTIONAL GROUP; QUINAZOLINE DERIVATIVE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ARTICLE; BRONCHODILATATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ACETYLCHOLINE; ANIMALS; BRIDGED COMPOUNDS; BRONCHODILATOR AGENTS; GUINEA PIGS; MUSCLE RELAXATION; MUSCLE, SMOOTH; NITROGEN; QUINAZOLINES; TRACHEA;

EID: 0036241665     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(02)01345-4     Document Type: Article

References (23)

1. The British Guidelines on Asthma Management: 1995 Review and Position Statement