Magnesium and manganese ions accelerate tissue factor-induced coagulation independently of factor IX

Blood Coagulation and Fibrinolysis

Volumn 13, Issue 1, 2002, Pages 19-23

  Van den Besselaar, A M H P ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Factor IX; Magnesium; Manganese; Prothrombin time; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 9; MAGNESIUM ION; MANGANESE; RECOMBINANT THROMBOPLASTIN;

ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TIME; CATTLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; RABBIT;

ANIMALS; BLOOD COAGULATION; CATTLE; DRUG INTERACTIONS; FACTOR IX; FACTOR X; HUMANS; KINETICS; MAGNESIUM; MANGANESE; PROTHROMBIN TIME; RABBITS; RECOMBINANT PROTEINS; THROMBOPLASTIN;

EID: 0036241577     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200201000-00003     Document Type: Article

References (14)

1. Role of γ-carboxyglutamic acid. Cation specificity of prothrombin and factor X-phospholipid binding
2. Interactions of vitamin K-dependent proteins with calcium ions and phospholipid membranes
3. 2+ ions
4. Prothrombin time ratio is reduced by magnesium contamination in evacuated blood collection tubes
5. Manganous ion and activation of prothrombokinase
6. An alternative extrinsic pathway of human blood coagulation
7. The role of factor IX in tissue thromboplastin induced coagulation
8. Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa
9. Effect of divalent metal ions on the binding of tissue factor and activated factor VII
10. Divalent cations and complex formation between tissue thromboplastin and factor VII
11. Manganese toxicity in children receiving long-term parenteral nutrition
12. Chronic manganese intoxication
13. Measurement of ionized magnesium with AVL 988/4 electrolyte analyzer: Preliminary analytical and clinical results