Prothrombin time ratio is reduced by magnesium contamination in evacuated blood collection tubes

Thrombosis and Haemostasis

Volumn 85, Issue 4, 2001, Pages 647-650

  Van Den Besselaar, A M H P ^a   Van Dam, W ^a   Sturk, A ^a   Bertina, R M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Blood collection; INR; Magnesium; Oral anticoagulant; Prothrombin time

Indexed keywords

CITRATE SODIUM; COUMARIN; MAGNESIUM CHLORIDE;

ACCURACY; ARTICLE; BIOMEDICAL TECHNOLOGY ASSESSMENT; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTAINER; CONTAMINATION; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DETERMINATION; HEMODYNAMIC MONITORING; HUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; STANDARDIZATION;

EID: 0035067666     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615647     Document Type: Article

References (15)

1. Effect of concentration of trisodium citrate anticoagulant on calculation of the international normalised ratio and the international sensitivity index of thromboplastin
2. Effect of 3.2% vs 3.8% sodium citrate concentration on routine coagulation testing
3. Effect of citrate concentration in specimen collection tubes on the international normalized ratio
4. Assessment of the influence of citrate concentration on the international normalized ratio (INR) determined with twelve reagent-instrument combinations
5. Effect of evacuated blood collection tubes on thromboplastin calibration
6. Different sensitivities of various thromboplastins to two blood collection systems for monitoring oral anticoagulant therapy
7. Measurement of prothrombin time in patients on oral anticoagulant therapy: Effect of two different evacuated tubes
8. A comparison of two sodium citrate concentrations in two evacuated blood collection systems for prothrombin time and ISI determination
9. Warfarin anticoagulation: Difficulties in interpretation of the prothrombin time
10. Magnesium(II) is a crucial constituent of the blood coagulation cascade
11. Expert Committee on Biological Standardization. Guidelines for thromboplastins and plasma used to control oral anticoagulant therapy
12. Minerals leached into drinking water from rubber stoppers
13. In vitro effects of trace elements on blood clotting and platelet function. B-Zinc and magnesium
14. Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa
15. Unsuitability of evacuated tubes for monitoring heparin therapy by activated partial thromboplastin time