Frequencies of 32 base pair deletion of the (Δ32) allele of the CCR5 HIV-1 co-receptor gene in Caucasians: A comparative analysis

Infection, Genetics and Evolution

Volumn 1, Issue 3, 2002, Pages 201-205

  Lucotte, Gérard ^a  

^a Center of Molecular Neurogenetics   (France)

Author keywords

32 allele frequencies; 32 mutation; CCR5 gene; HIV 1; Middle East and North Africa; Populations in Europe; Variola virus; Viking origin

Indexed keywords

CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR;

ARTICLE; BASE PAIRING; CAUCASIAN; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA EXTRACTION; GENE DELETION; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC CODE; HOMOZYGOSITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; NONHUMAN; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PRIORITY JOURNAL; RECEPTOR GENE; SMALLPOX VIRUS; VIRUS STRAIN; COMPARATIVE STUDY; GENETICS; METABOLISM;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; VARIOLA; VARIOLA VIRUS;

EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; HIV INFECTIONS; HUMANS; RECEPTORS, CCR5; SEQUENCE DELETION;

EID: 0036240861     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-1348(02)00027-8     Document Type: Article

References (25)

1. Mutational analysis of the CCR5 and CXCR4 genes (HIV-1 co-receptors) in resistance to HIV-1 infection and AIDS development among intravenous drug users
2. 2001 Contrasting frequencies of CCR5Δ32 and CCR2-641 alleles in the Tunisian population
3. Distribution of the CCR5Δ32 allele in Italian type 1-infected and normal individuals
4. Alpha-1 anti-trypsin P1 phenotypes S and Z in Europe: An analysis of the published surveys
5. Low frequencies of CCR5Δ32 allele among Greeks in Cyprus
6. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
7. Frequency of the CCR5Δ32 allele in the Moroccan population
8. History of Vikings
9. Use of chemokine receptors by proxviruses
10. The CCR5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in north-eastern Europe
11. Homozygous defect in HIV-1 co-receptors accounts for resistance of some multiply-exposed individuals to HIV-1 infection
12. Frequencies of the CC chemokine receptor 5 Δ32 allele in various populations of defined racial background
13. Frequency analysis and allele map in favor of the Celtic origin of the C282Y mutation of hemochromatosis
14. Δ32 Mutation frequencies of the CCR5 co-receptor in different French regions
15. Distributions of the CCR5 gene 32 bp deletion in Europe
16. Distribution of the CCR5 gene 32 base pair deletion and SDF 1-3′A variant in healthy individuals from different populations
17. Global distribution of the CCR5 gene 32 base pair deletion
18. Spectrofluorimetric analysis of CCR5Δ32 allele using real-time polymerase chain reaction: Prevalence in southern spanish HIV+ patients and non-infected population
19. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR5 chemokine receptor gene
20. Dating the origin of the CCR5Δ32 AIDS-resistance allele by the coalescence of haplotypes
21. Prevalences of CCR5 and CCR2 HIV-co-receptor gene polymorphisms in Belgium
22. A survey for 32 nucleotide deletion in the CCR5 chemokine receptor gene (Dccr-5) conferring resistance to human immunodeficiency virus type 1 in different ethnic groups and in chimpanzees
23. Frequency of a mutated CCR5 allele (Δ32) among italian healthy donors and individuals at risk of parenteral HIV infection
24. Inherited resistance to HIV-1 conferred by an inactivating mutation in the CC chemokine receptor 5; studies in populations with contrasting clinical phenotypes, defined by racial background, and quantified risk