메뉴 건너뛰기




Volumn 3, Issue 4, 2002, Pages 443-454

Oxybutynin chloride: Alterations in drug delivery and improved therapeutic index

Author keywords

Oxybutynin chloride; Pharmacotherapy; Urinary incontinence

Indexed keywords

CYTOCHROME P450 3A4; DESETHYLOXYBUTYNIN; DRUG METABOLITE; MUSCARINIC RECEPTOR BLOCKING AGENT; OXYBUTYNIN; PHENYLCYCLOHEXYLGLYCOLIC ACID; PLACEBO; TOLTERODINE; UNCLASSIFIED DRUG; WATER; MANDELIC ACID DERIVATIVE;

EID: 0036240759     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.3.4.443     Document Type: Review
Times cited : (10)

References (46)
  • 6
    • 0029265229 scopus 로고
    • Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability
    • (1995) Drugs Aging , vol.6 , Issue.3 , pp. 243-262
    • Yarker, Y.E.1    Goa, K.L.2    Fitton, A.3
  • 10
    • 0001855098 scopus 로고    scopus 로고
    • Pharmacological profile of DDO1 and desethyloxybutynin (DEOB) - The major metabolite of tolterodine and oxybutynin (OB) respectively
    • (1997) J. Urol , vol.157 , pp. 81-84
    • Gillberg, P.1    Steffan, S.2
  • 11
    • 0026782156 scopus 로고
    • Measurement of oxybutynin and its N-desethyl metabolite in plasma and its application in pharmacokinetic studies in young, elderly, and frail elderly volunteers
    • (1992) Xenobiotica , vol.22 , Issue.7 , pp. 859-869
    • Hughes, K.M.1    Lang, J.C.2    Lazare, R.3
  • 15
    • 0031471714 scopus 로고    scopus 로고
    • Clinical efficacy and safety of tolterodine in the treatment of overactive bladder: A pooled analysis
    • (1997) Urology , vol.50 , pp. 91-96
    • Appell, R.A.1
  • 25
    • 0028973686 scopus 로고
    • Intravesical application of oxybutynin: Mode of action in controlling detrusor hyperreflexia. Preliminary results
    • (1995) Eur. Urol , vol.28 , Issue.4 , pp. 340-344
    • Madersbacher, H.1    Knoll, M.2
  • 30
    • 0003595611 scopus 로고    scopus 로고
    • The effect of pH on drug release from extended release formulations of oxybutynin and tolterodine
    • 2nd International Consultation on Incontinence. Paris, France (1-3 July )
    • (2001)
    • Dmochowski, R.1    Sathyan, G.2    Ye, C.3    Gupta, S.K.4
  • 32
    • 0032978860 scopus 로고    scopus 로고
    • Pharmacokinetics of an oral once a day controlled release oxybutynin formulation compared with immediate release oxybutynin
    • (1999) J. Clin. Pharmacol , vol.39 , pp. 289-296
    • Gupta, S.K.1    Sathyan, G.2
  • 40
    • 0035088137 scopus 로고    scopus 로고
    • Prospective randomized controlled trial of extended release oxybutynin chloride and tolterodine tartrate in the treatment of overactive bladder: Results of the OBJECT trial
    • (2001) Mayo Clin. Proc , vol.76 , pp. 358-363
    • Appell, R.A.1    Sand, P.2    Dmochowski, R.3
  • 42
    • 0034091838 scopus 로고    scopus 로고
    • A randomized controlled trial comparing the efficacy of controlled release oxybutynin tablets (10 gm once daily) with conventional oxybutynin tablets (5 mg twice daily) in patients whose symptoms were of oxybutynin
    • (2000) Br. J. Urol , vol.85 , pp. 793-798
    • Birns, J.1    Lukkari, E.2    Malone-Lee, J.G.3
  • 44
    • 4243392089 scopus 로고    scopus 로고
    • One year, prospective, open label trial of controlled release oxybutynin for overactive bladder in a community based population
    • American Geriatric Society Poster
    • (2000)
    • Appell, R.1    Diokno, A.2    Antoci, J.3    Labasky, R.4
  • 45
    • 4243723801 scopus 로고    scopus 로고
    • Controlled release oxybutynin for overactive bladder in an elderly population
    • American Geriatric Society Poster
    • (2000)
    • Tuttle, J.1    Antoci, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.