Nipradilol can prevent left ventricular systolic and diastolic dysfunction after myocardial infarction in rats

Circulation Journal

Volumn 66, Issue 3, 2002, Pages 289-293

  Satoru, Izutani ^a   Minoru, Yoshiyama ^a   Takashi, Omura ^a   Ken, Yoshida ^a   Yasuhiro, Nakamura ^a   Shokei, Kim ^b   Kazuhide, Takeuchi ^a   Junichi, Yoshikawa ^a  

^a Departments of Internal Medicine and Cardiology

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

blocker; Cardiac remodeling; Doppler echocardiography; Myocardial infarction; Systolic and diastolic function

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; MESSENGER RNA; NIPRADILOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIOLOGICAL MARKER; PROPANOLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOPPLER ECHOGRAPHY; DRUG EFFECT; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FAILURE; HEART VENTRICLE REMODELING; HEMODYNAMICS; MALE; NONHUMAN; ORGAN WEIGHT; PROTEIN EXPRESSION; RAT; ANIMAL; DISEASE MODEL; DOPPLER ECHOCARDIOGRAPHY; GENETICS; HEART LEFT VENTRICLE FUNCTION; METABOLISM; PATHOLOGY; WISTAR RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL MARKERS; COLLAGEN TYPE I; COLLAGEN TYPE III; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY, DOPPLER; MYOCARDIAL INFARCTION; NATRIURETIC PEPTIDE, BRAIN; PROPANOLAMINES; RATS; RATS, WISTAR; RNA, MESSENGER; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 0036238790     PISSN: 13469843     EISSN: None     Source Type: Journal    
DOI: 10.1253/circj.66.289     Document Type: Article

References (31)

1. Left ventricular remodeling after myocardial infarction: A corollary to infarct expansion
2. Ventricular remodeling after myocardial infarction: Experimental observations and clinical implications
3. Global cardiac remodeling after acute myocardial infarction: A study in the rat model
4. Time course of left ventricular remodeling after myocardial infarction: A two-dimensional echocardiographic study
5. Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
6. Survival after an experimental myocardial infarction: Beneficial effects of long-term therapy with captopril
7. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the survival and ventricular enlargement trial
8. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
9. Effects of candesartan and cilazapril on rats with myocardial infarction assessed by echocardiography
10. Subgroup findings from randomized trials in post infarction patients
11. Retrospective analysis showing less cardiac events in post-myocardial infarction patients treated with metoprolol
12. Beta blockade during and after myocardial infarction: An overview of the randomized trials
13. Long-term propranolol administration alters myocyte and ventricular geometry in rat hearts with and without infarction
14. Chronic propranolol treatment promotes left ventricular dilation without altering systolic function after large myocardial infarction in rats
15. Effect of prolonged beta-adrenergic blockade induced by atenolol on left ventricular remodeling after acute myocardial infarction in the rat
16. Venodilating action of nipradilol (K-351) in the pithed rat pretreated with dihydroergotamine
17. Vasoactive and beta- adrenoceptor blocking properties of 3,4-dihydro-8-(2-hydroxy-3-isopropylamino) propoxy-3-nitroxy-2H-1-benzopyran (K-351), a new antihypertensive agent
18. Chronic therapy with nipradilol, a beta-adrenergic blocker, attenuated left ventricular remodeling following myocardial infarction in rats
19. Nipradilol, A new beta-adrenergic blocker, reduces left ventricular remodeling following myocardial infarction in spontaneously hypertensive rats
20. 2+ exchanger genes between adjacent and remote noninfarcted myocardium after myocardial infarction
21. Serial echocardiographic assessment of left ventricular geometry and function after large myocardial infarction in the rat
22. Early and late effects of captopril treatment after large myocardial infarction in rats
23. Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats
24. Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction
25. Antiremodeling effects on the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure
26. Importance of collateral circulation for prevention of left ventricular aneurysm formation in acute myocardial infarction
27. Importance of venodilatation in prevention of left ventricular dilatation after chronic large myocardial infarction in rats: A comparison of captopril and hydralazine
28. Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload
29. Inhibition of collagen cross-linking: Effects on fibrillar collagen and ventricular diastolic function
30. Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium
31. Effect of cilazapril on ventricular remodeling assessed by Doppler-echocardiographic assessment and cardiac gene expression