Chronic therapy with nipradilol, a β-adrenergic blocker, attenuated left ventricular remodeling following myocardial infarction in rats

Japanese Journal of Pharmacology

Volumn 74, Issue 2, 1997, Pages 171-178

  Sonoki, Hiroyuki ^a   Nakamura, Masaki ^a   Takeshita, Akira ^b  

^a KOWA COMPANY LTD   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Cardiac function; Left ventricular diastolic volume; Myocardial infarction; Nipradilol; Remodeling

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; NIPRADILOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HEART INDEX; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE PRESSURE; HEART PERFORMANCE; HEART RATE; HEMODYNAMICS; MEAN ARTERIAL PRESSURE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SYSTEMIC VASCULAR RESISTANCE;

EID: 0030857139     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.74.171     Document Type: Article

References (26)

1. Pfeffer JM, Pfeffer MA, Fletcher PJ and Braunwald E: Progressive ventricular remodeling in rats with myocardial infarction. Am J Physiol 261, H1406-H1414 (1991)
2. Vaughan DE and Pfeffer MA: Post-myocardial infarction ventricular remodeling: Animal and human studies. Cardiovasc Drug Ther 8, 453-460 (1994)
3. White HD, Norris RM, Brown MA, Brandt PWT, Whitlock RHL and Wild CJ: Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 76, 44-51 (1987)
4. Pfeffer JM, Pfeffer MA and Braunwald E: Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 57, 84-95 (1985)
5. Pfeffer MA, Lamas GA and Vaughan DE: Effect of captopril on progressive ventricular dilation after anterior myocardial infarction. N Engl J Med 319, 80-86 (1988)
6. Nishikimi T, Yamagishi H, Takeuchi K and Takeda T: An angiotensin II receptor antagonist attenuates left ventricular dilation after myocardial infarction in the hypertensive rat. Cardiovasc Res 29, 856-861 (1995)
7. McDonald KM, Francis GS, Matthews J, Hunter D and Cohn JN: Long-term oral nitrate therapy prevents chronic ventricular remodeling in the dog. J Am Coll Cardiol 21, 514-522 (1993)
8. Jugdutt BI and Khan MI: Effect of prolonged nitrate therapy on left ventricular remodeling after canine acute myocardial infarction. Circulation 89, 2297-2307 (1994)
9. Yusuf S, Peto R, Lewis J, Collins R and Sleight P: Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 27, 335-371 (1985)
10. The Beta-Blocker Pooling Project Research Group: The Beta-Blocker Pooling Project (BBPP): subgroup findings from randomized trials in postinfarction patients. Eur Heart J 9, 8-16 (1988)
11. Fishbein MC, Lei L-Q and Rubin SA: Long-term propranolol administration alters myocyte and ventricular geometry in rats hearts with and without infarction. Circulation 78, 369-375 (1988)
12. Gay RG, Raya TE and Goldman S: Chronic propranolol treatment promotes left ventricular dilation without altering systolic function after large myocardial infarction in rats. J Cardiovasc Pharmacol 16, 529-536 (1990)
13. Uchida Y, Nakamura M, Shimizu S, Shirasawa Y and Fujii M: Vasoactive and β-adrenoceptor blocking properties of 3,4-dihydro-8(2-hydroxy-3-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran (K-351), a new antihypertensive agent. Arch Int Pharmacodyn Ther 262, 132-149 (1983)
14. Shirasawa Y, Fujii M and Nakamura M: Venodilating action of nipradilol (K-351) in the pithed rat pretreated with dihydroergotamine. Jpn J Pharmacol 39, 77-82 (1985)
15. Ebihara A, Kondo K and Ohashi K: Pharmacodynamic and pharmacological effects of nipradilol (K-351) in healthy volunteers. - comparison with propranolol -. Jpn J Clin Pharmacol Ther 17, 391-401 (1986) (Abstr in English)
16. Nakanishi T, Nishimura M, Kubota S and Hirabayashi M: Effects of nipradilol on 24-hour blood pressure in patients with essential hypertension. Curr Ther Res 48, 198-205 (1990) (Abstr in English)
17. Selye H, Bajusz E, Grasso S and Mendell P: Simple techniques for the surgical occlusion of coronary vessels in the rat. Angiology 11, 398-407 (1960)
18. Fletcher PJ, Pfeffer JM, Pfeffer MA and Braunwald E: Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function. Circ Res 49, 618-626 (1981)
19. Gaasch WH, Levine HJ, Quinones MA and Alexander JK: Left ventricular compliance: Mechanisms and clinical implications. Am J Cardiol 38, 645-653 (1976)
20. Mirsky I: Assessment of passive elastic stiffness of cardiac muscle: mathematical concepts, physiologic and clinical considerations, directions of future research. Prog Cardiovasc Dis 18, 277-308 (1976)
21. McKay RG, Pfeffer MA, Pasternak RC, Markis JE, Come PC, Nakao S, Alderman, JD, Ferguson JJ, Safian RD and Grossman W: Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion. Circulation 74, 693-702 (1986)
22. Weber KT and Brilla CG: Pathological hypertrophy and cardiac interstitium: fibrosis and renin-angiotensin-aldosterone system. Circulation 83, 1849-1865 (1991)
23. Hirai T, Fujita M, Nakajima H, Asanoi H, Yamanishi K, Ohno A and Sasayama S: Importance of collateral circulation for prevention of ventricular aneurysm formation in acute myocardial infarction. Circulation 79, 791-796 (1989)
24. Raya TH, Gay RG, Aguirre M and Goldman S: Importance of venodilation in prevention of left ventricular dilation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine. Circ Res 64, 330-337 (1989)
25. Olivetti G, Capasso JM, Meggs LG and Sonnenblick EH: Cellular basis of chronic ventricular remodeling after myocardial infarction in rats. Circ Res 68, 856-869 (1991)
26. Weissman HF, Bush DE, Mannist JA, Weisfeldt ML and Healy B: Cellular mechanisms of myocardial infarct expansion. Circulation 76, 186-201 (1988)