Impact of aldosterone on vascular pathophysiology

Congestive Heart Failure

Volumn 8, Issue 1, 2002, Pages 18-22

  Struthers, Allan D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ALDOSTERONE; ANGIOTENSIN; ANTILIPEMIC AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; N(G) METHYLARGININE; NITROPRUSSIDE SODIUM; OUABAIN; SPIRONOLACTONE;

ADRENERGIC SYSTEM; ANIMAL MODEL; AUTONOMIC NERVOUS SYSTEM; CARDIOVASCULAR DISEASE; DRUG EFFECT; FOREARM BLOOD FLOW; GENOME; HEART FAILURE; HEART MUSCLE FIBROSIS; HUMAN; HYPERLIPIDEMIA; NONHUMAN; PATHOPHYSIOLOGY; PRESSORECEPTOR REFLEX; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; REVIEW; VAGUS NERVE; VASCULAR ENDOTHELIUM;

EID: 0036234925     PISSN: 10797998     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-5299.2002.00722.x     Document Type: Review

References (9)

1. Regulation of aldosterone synthase in human vascular cells by AII and ACTH
2. Aldosterone inhibits nitric oxide synthesis in rat vascular smooth muscle cells induced by interleukin-1 β
3. Spironolactone increases NO bioactivity, improves endothelial dysfunction and suppresses vascular AI/AII conversion in chronic heart failure
4. Inverse relationship between aldosterone and large artery compliance in chronically treated heart failure patients
5. Synergistic effect of adrenal steroids and'angiotensin II on plasminogen activator inhibitor-1 production
6. Mineralocorticoid blockade reduces vascular injury in stroke prone hypertensive rats
7. Pathological hypertrophy and cardiac interstitium: Fibrosis and renin angiotensin aldosterone system
8. Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
9. Role of NO in the regulation of cardiovascular autonomic control