Gene therapy: New "magic bullets" to prevent ocular scarring

British Journal of Ophthalmology

Volumn 86, Issue 5, 2002, Pages 490-492

  Khaw, P T ^a   Cambrey, A D ^a   Limb, G A ^a   Daniels, J T ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE DEAMINASE; FLUOROURACIL; HEPARIN; VIRUS VECTOR;

ADENOVIRUS; BLINDNESS; EDITORIAL; ENDOPHTHALMITIS; EYE DISEASE; EYE TOXICITY; GENE THERAPY; GLAUCOMA; HUMAN; PRIORITY JOURNAL; RETINA MACULA DEGENERATION; SCAR FORMATION; VITREORETINOPATHY;

CICATRIX; EYE DISEASES; GENE THERAPY; HUMANS;

EID: 0036234048     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.86.5.490     Document Type: Editorial

References (14)

1. The Advanced Glaucoma Intervention Study (AGIS) 7. The relationship between control of intraocular pressure and visual field deterioration
2. Adenoviral-mediated gene transfer to the filtering bleb in rabbits
3. 5-Minute treatments with fluorouracil, floxuridine and mitomycin have long-term effects on human Tenon's capsule fibroblasts
4. Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases
5. Lentiviral vectors: Turning a deadly foe into a therapeutic agent
6. Gene therapy: Into the future of surgery
7. Human gene therapy
8. Activation and suppression of fibroblast activity
9. Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa
10. Human anti-transforming growth factor-beta2 antibody: A new glaucoma anti-scarring agent
11. A randomised double-masked placebo-contolled trial of human anti-TGFbeta2 monaclonal antibody (CAT-152): A potential new modulator of wound healing following trabeculectomy
12. Cystic bleb related complications in limbus versus fornix based flaps in paediatric and young adult trabeculectomy with high dose mitomycin C
13. Effects of single, short-term exposures of human retinal pigment epithelial cells to thiotepa or 5-fluorouracil: Implications for the treatment of proliferative vitreoretinopathy
14. Adjuvant 5-fluorouracil and heparin prevents proliferative vitreoretinopathy: Results from a randomised double blind controlled clinical trial