Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat

Anesthesiology

Volumn 96, Issue 5, 2002, Pages 1153-1160

  Bosnjak, Zeljko J ^c   Pogatzki, Esther M ^a   Urban, Mark O ^b   Brennan, Timothy J ^b   Gebhart, Gerald F ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c College of Medicine ^*

Author keywords

[No Author keywords available]

Indexed keywords

IBOTENIC ACID; NEUROTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FACILITATION; GASTROCNEMIUS MUSCLE; HYPERALGESIA; INCISION; INFLAMMATION; LEG MUSCLE; MALE; MECHANICAL STIMULATION; MEDULLA OBLONGATA; MUSCLE INJURY; NEUROPATHY; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; RAT; WITHDRAWAL REFLEX;

ANIMALS; BEHAVIOR, ANIMAL; EXCITATORY AMINO ACID AGONISTS; FOOT; HEAT; HINDLIMB; HYPERALGESIA; IBOTENIC ACID; MALE; MEDULLA OBLONGATA; MUSCLE, SKELETAL; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; STIMULATION, CHEMICAL;

EID: 0036233945     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200205000-00019     Document Type: Article

References (42)

1. Effects of an experimental arthritis on the sensory properties of fine articular afferent units
2. Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee
3. Behavioral and immunohistochemical changes in an experimental arthritis model in rats
4. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
5. Peptides and the primary afferent nociceptor
6. The molecular pathophysiology of pain: Abnormal expression of sodium channel genes and its contributions to hyperexcitability of primary sensory, neurons
7. Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence
8. Transcriptional and posttranslational plasticity and the generation of inflammatory pain
9. Supraspinal contributions to hyperalgesia
10. Central mechanisms in pain
11. Characterization of a rat model of incisional pain
12. Primary and secondary hyperalgesia in a rat model of postoperative pain
13. Characterization of A-delta and C-fibers innervating the plantar rat hindpaw one day after an incision
14. Incision-induced changes in receptive field properties of rat dorsal horn neurons
15. Effect of pretreatment with intrathecal excitatory amino acid receptor antagonists on the development of pain behavior caused by a plantar incision
16. Lack of effect of intrathecal NMDA receptor antagonists in a rat model for postoperative pain
17. Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain
18. Intrathecal metabotropic glutamate receptor antagonists do not decrease mechanical hyperalgesia in a rat model of postoperative pain
19. Secondary hyperalgesia after gastrocnemius incision in the rat
20. Ethical guidelines for investigations of experimental pain in conscious animals
21. Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat
22. The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat
23. A method for determining loss of pain sensation
24. Participation of central descending nociceptive facilitatory systems in secondary hyperalgesia produced by mustard oil
25. Central nervous system mechanisms of pain modulation
26. Neurotransmitters in nociceptive modulatory circuits
27. Endogenous pain facilitory systemsantianalgesia and hyperalgesia
28. Inhibition and facilitation of different nocifensor reflexes by spatially remote noxious stimuli
29. Neurocircuitry of illness-induced hyperalgesia
30. Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia
31. Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat
32. Supraspinal influence on hindlimb withdrawal thresholds and mustard oil-induced secondary allodynia in rats
33. A neuronal correlate of secondary hyperalgesia in the rat spinal dorsal horn is submodality selective and facilitated by supraspinal influence
34. Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats
35. Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil
36. Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade
37. Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation
38. Diffuse noxious inhibitory controls (DNIC) in animals and in man
39. Changes in tonic descending inhibition of spinal neurons with articular input during the development of acute arthritis in the cat
40. Enhanced descending modulation of nociception in rats with persistent hindpaw inflammation
41. Illness-induced hyperalgesia is mediated by a spinal NMDA-nitric oxide cascade