In vitro and in vivo study in rats of rectal suppositories containing furosemide

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 53, Issue 3, 2002, Pages 311-315

  Berkó, Szilvia ^a   Regdon Jr , Géza ^a   Ducza, Eszter ^a   Falkay, George ^a   Eros, István ^a,b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Cremophor RH 60; Diuretic effect; Furosemide; Montanox 60 DF; Rat; Solutol HS 15; Suppository

Indexed keywords

CREMOPHOR; FUROSEMIDE; MASSA ESTARINUM B; MASSA ESTARINUM BC; MONTANOX 60DF; SOLUTOL HS 15; SORBITAN OLEATE; SUPPOCIRE; SUPPOCIRE AML; SUPPOCIRE AP; SUPPOCIRE AS2X; SUPPOSITORY BASE; SURFACTANT; UNCLASSIFIED DRUG; WITEPSOL H 15; WITEPSOL W 35;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIFFUSION; DIURESIS; DRUG RELEASE; IN VITRO STUDY; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; RAT; RECTAL DRUG ADMINISTRATION; SUPPOSITORY;

ADMINISTRATION, RECTAL; ANIMALS; DIFFUSION; DIURESIS; DIURETICS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FUROSEMIDE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SUPPOSITORIES; SURFACE-ACTIVE AGENTS; VEHICLES;

EID: 0036221723     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00005-X     Document Type: Article

References (23)

1. Enhancement of bioavailability of griseofulvin by its complexation with beta-cyclodextrin
2. The effect of 2-hydroxypropyl-beta-cyclodextrin on in vitro drug release of steroids from suppository bases
3. Bioavailability of diazepam from aqueous-organic solution, submicron emulsion and solid lipid nanoparticles after rectal administration in rabbits
4. In vitro study of rectal suppositories containing metronidazole and their use in humans
5. Utility of rectal suppository containing the antiepileptic drug zonisamide
6. In vitro properties of ciprofloxacin suppositories formulated with glycerogelatin and theobroma oil bases
7. Improvement of availability of allopurinol from pharmaceutical dosage forms I - suppositories
8. Evaluation of paracetamol suppositories by a pharmacopoeial dissolution test - comments on methodology
9. Gastrointestinal sites of furosemide absorption in rats
10. Pharmacokinetics of furosemide in man after intravenous and oral administration. Application of moment analysis
11. Formulation and in vitro examination of furosemide containing suppositories and preliminary experiences of their clinical use
12. An in-vivo-in-vitro correlation for the bioavailability of furosemide tablets
13. Preparation and in vitro study of suppositories containing No-Spa. II. Determination of release of the active principle by membrane diffusion methods
14. Effects of bases and additives on release of carbon dioxide from effervescent suppositories
15. On the action of various factors on the liberation from suppositories
16. Influence of the hydrophilicity of suppository bases on rectal absorption of carprofen, a lipophilic nonsteroidal anti-inflammatory drug
17. Gastrointestinal first-pass effect of furosemide in rats
18. Radiolabelling of parenteral O/W emulsions by means of neutron activation
19. Effect of quercetin, caffeic acid and caffeic acid phenylethyl ester, solubilized in non-ionic surfactants, on histamin release in vivo and in vitro
20. The influence of alkali fatty acids on the properties and stability of parenteral o/w emulsions modified with Solutol HS 15
21. The use of surfactants to enhance the permeability of peptides through caco-2 cells by inhibition of an apically polarized efflux system