Rat small hepatocytes for liver support: Growth and metabolic activities in culture

Journal of Artificial Organs

Volumn 5, Issue 1, 2002, Pages 24-29

  Kamachi, H ^a   Matsushita, M ^a   Okubo, H ^a   Kawai, T ^a   Nishikawa, K ^b   Fujimoto, T ^b   Todo, S ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Albumin; Culture; Proliferation; Small hepatocyte

Indexed keywords

ALBUMIN; COLLAGEN; DIMETHYL SULFOXIDE; DNA; NICOTINAMIDE; RETINOIC ACID; UREA;

ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; CELL DENSITY; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CELL VIABILITY; CENTRIFUGATION; CONTROLLED STUDY; CULTURE MEDIUM; DENSITY GRADIENT; DNA CONTENT; GLUCONEOGENESIS; IN VITRO STUDY; LIVER CELL CULTURE; LIVER PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; UREA CYCLE;

EID: 0036218886     PISSN: 14347229     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100470200004     Document Type: Article

References (17)

1. Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial
2. Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation
3. Safety and feasibility of liver directed ex vivo gene therapy for homozygous familial hypercholesterolemia
4. Effect of a hybrid liver support system on cardiopulmonary function in healthy pigs
5. Infection by porcine endogenous retrovirus after islet xenotrasnplantation in SCID mice
6. Hepatocytes transplantation as a bridge to orthotopic liver transplantation in terminal liver failure
7. Fractionation of rat hepatocyte subpopulations with varying metabolic potential, proliferative capacity, and retroviral gene transfer efficiency
8. Small cell colonies appear in the primary culture of adult rat hepatocytes in the presence of nicotinamide and epidermal growth factor
9. Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonoparenchymal cells
10. Long-term maintenance of hepatocytes in primary culture in the presence of DMSO: Further characterization and effect of nafenopin, a peroxisome proliferator
11. Retinoids and their receptors in differentiation, embryogenesis and neoplasia
12. 9-Cis retinoic acid is a direct hepatocyte mitogen in rats
13. Assay for nanogram quantities of DNA in cellular homogenates
14. Automated and manual direct methods for the determination of blood urea
15. Use of glucose oxidase, peroxidase and odianidine in determination of blood and urinary glucose
16. Heterogeneity of growth potential of adult rat hepatocytes in vitro
17. Hepatocyte transplantation for enzyme deficiency disease in congenic rats