Urocortin-induced endothelium-dependent relaxation of rat coronary artery: Role of nitric oxide and K+ channels

British Journal of Pharmacology

Volumn 135, Issue 6, 2002, Pages 1467-1476

  Huang, Yu ^a   Chan, Franky Leung ^a   Lau, Chi Wai ^a   Tsang, Suk Ying ^a   He, Guo Wei ^a   Chen, Zhen Yu ^a   Yao, Xiaoqiang ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Barium; Coronary artery; Endothelium; Nitric oxide; Rat; Urocortin

Indexed keywords

ARGININE METHYL ESTER; BARIUM CHLORIDE; BARIUM ION; CYCLIC GMP; HYDROXYLAMINE; INDOMETACIN; METHYLENE BLUE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; OUABAIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; UROCORTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM; IMMUNOREACTIVITY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CORONARY VESSELS; CORTICOTROPIN-RELEASING HORMONE; ENDOTHELIUM, VASCULAR; MALE; MUSCLE, SMOOTH, VASCULAR; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; VASODILATION;

EID: 0036218308     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704587     Document Type: Article

References (43)

1. Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway
2. CRH-like peptides protect cardiac myocytes from lethal ischaemic injury
3. Proteoglycans associated with the ciliary zonule of the rat eye: A histochemical and immunocytochemical study
4. Expression cloning of a human corticotropin-releasing-factor receptor
5. Corticotropin-releasing hormone-induced vasodilatation in the human fetal placental circulation
6. Corticotropin-releasing hormone-induced vasodilatation in the human fetal-placental circulation: Involvement of the nitric oxide-cyclic guanosine 3′,5′-monophosphate-mediated pathway
7. + is an endothelium-derived hyperpolarizing factor in rat arteries
8. Sauvagine, a new polypeptide from Phyllomedusa sauvagei skin. Occurrence in various Phyllomedusa species and pharmacological actions on rat blood pressure and diuresis
9. Effects of corticotropin-releasing factor on isolated rat heart activity
10. Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells
11. + channel blockers in rat aortic rings
12. Urocortin, a newly identified corticotropin-releasing factor-related mammalian peptide, stimulates atrial natriuretic peptide and brain natriuretic peptide secretions from neonatal rat cardiomyocytes
13. The relaxation responses to corticotropin-releasing factor in rat aorta are endothelium dependent and gestationally regulated
14. Endothelium-dependent and -independent mechanisms of vasorelaxation by corticotropin-releasing factor in pregnant rat uterine artery
15. + channel inhibition by tertiapin-Q
16. Sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle
17. + channels in rabbit cardiac myocytes
18. Intra- and extracerebral blood flow changes and flushing after intravenous injection of human corticotropin-releasing hormone
19. Relaxing actions of corticotropin-releasing factor on rat resistance arteries
20. Vasodilator actions of urocortin and related peptides in the human perfused placenta in vitro
21. Corticotropin-releasing factor, sauvagine, and urotensin I: Effects on blood flow
22. CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues
23. Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain
24. Ca) in smooth muscle cells isolated from the rat mesenteric artery
25. Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart
26. Physiological roles and properties of potassium channels in arterial smooth muscle
27. Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors
28. Cardiac inotropic actions of urocortin in conscious sheep
29. Urotensin II: A somatostatin-like peptide in the caudal neurosecretory system of fishes
30. Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart
31. + currents
32. Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary
33. Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors
34. Comparison of hCRF and oCRF effects on cardiovascular responses after central, peripheral, and in vitro application
35. 2+
36. Characterization of the relaxant action of urocortin, a new peptide related to corticotropin-releasing factor in the rat isolated basilar artery
37. + channels in arterial smooth muscle
38. Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart
39. Coronary vasodilation and positive unotropism by urocortin in the isolated rat heart
40. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
41. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
42. Barium inhibits the endothelium-dependent component of flow but not acetylcholine-induced relaxation in isolated rabbit cerebral arteries
43. The properties of the inward rectifier potassium currents in rabbit coronary arterial smooth muscle cells