Elimination of levofloxacin in critically ill patients with renal failure: Influence of continuous veno-venous hemofiltration

International Journal of Clinical Pharmacology and Therapeutics

Volumn 40, Issue 4, 2002, Pages 142-149

  Bellmann, R ^a   Egger, P ^a   Gritsch, W ^a   Bellman Weiler, R ^a   Joannidis, M ^a   Dunzendorfer, S ^a   Wiedermann, C J ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Hemofiltration; Intensive care unit; Levofloxacin; Pharmacokinetics; Renal failure

Indexed keywords

LEVOFLOXACIN; OFLOXACIN; POLYSULFONE;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL ILLNESS; DISEASE SEVERITY; DISTRIBUTION VOLUME; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BINDING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFUSION; FEMALE; HEMOFILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFECTION; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; MEAN RESIDENCE TIME; MEMBRANE BINDING; MEMBRANE FILTER; SEPTIC SHOCK;

EID: 0036216845     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP40142     Document Type: Article

References (30)

1. A randomized, crossover design study of the pharmacology of extended-spectrum fluoroquinolones for pneumococcal infections
2. Clinical pharmacology and efficacy of levofloxacin in elderly patients
3. Pharmacokinetics of ofloxacin in severe chronic renal failure
4. Clinical pharmacokinetics during continuous haemofiltration
5. Absence of age and gender effects on the pharmacokinetics of a single 500 milligram oral dose of levofloxacin in healthy subjects
6. Pharmacokinetic profile of levofloxacin following once-daily 500 milligram oral or intravenous doses
7. Double-blind evaluation of the safety and pharmacokinetics of multiple oral once-daily 750 milligram and 1 gram doses of levofloxacin in healthy volunteers
8. Pharmacokinetics of levofloxacin in healthy Thai male volunteers
9. Prediction of creatinine clearance from serum creatinine
10. Pharmacokinetics of quinolones in renal insufficiency
11. The clinical pharmacokinetics of levofloxacin
12. The pharmacokinetic of levofloxacin in subjects with renal impairment, and in subjects receiving hemodialysis or continuous ambulatory peritoneal dialysis
13. Drug removal during continuous arteriovenous hemofiltration: Theory and clinical observations
14. Pharmacokinetics of levofloxacin during veno-venous hemofiltration
15. Solute clearance in continuous venovenous hemodialysis. A comparison of cuprophane, polyacrylonitrile, and polysulfone membranes
16. Drug administration in critically ill patients with acute renal failure
17. Elimination of drugs by the new polyamide hemofilter FH77H during various in vitro conditions
18. Ofloxacin pharmacokinetics in chronic renal failure and dialysis
19. Pharmacodynamics of levofloxacin and ciprofloxacin against Streptococcus pneumoniae
20. The pharmacokinetics of once-daily oral 400 mg ofloxacin in patients with peritonitis complicating continuous ambulatory peritoneal dialysis
21. Phase I study of levofloxacin, (S)-(-)-ofloxacin
22. Levofloxacin, a second-generation fluoroquinolone
23. Single- and multiple-dose kinetics of ofloxacin in patients on continuous ambulatory peritoneal dialysis (CAPD)
24. Pharmacokinetics of levofloxacin in patients with impaired renal function
25. Pharmacokinetics of continuous renal replacement therapy
26. Ofloxacin clearance during hemodialysis: A comparison of polysulfone and cellulose acetate hemodialyzers
27. Single-dose pharmacokinetics of levofloxacin during continuous veno-venous haemofiltration in critically ill patients
28. Solute transport in hemodiafiltration: A new mathematical model to analyze dialyzer performance
29. The pharmacokinetics of ofloxacin, desmethyl ofloxacin and ofloxacin N-oxide in haemodialysis patients with end-stage renal failure
30. Levofloxacin: A therapeutic review